aspartimide

formed under acid or basic conditions in the synthesis of aspartic acid-containing peptides

Also Known As:

2,5-Pyrrolidinedione, 3-amino-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 07/01/2010 - "[Abu6]TSPB and [Abu6]TSPA, aspartimide analogs of natural sequences of TSP-1 and TSP-2, respectively, were tested for adhesion of tumor and endothelial cells, in vivo and in vitro antiangiogenic effects, and in vivo antitumor action. "
2.	Dehydration (Water Stress) 01/01/1995 - "The peptide contaminant was 17-18 Da smaller than the parent peptide consistent with a modified asparagine residue at position 6 and so we synthesised both an aspartimide and a nitrile analogue, representing cyclisation or dehydration of the asparagine residue. "