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eIF-4

contributes to the rise in protein synthetic rate in cell-free translation systems of sea urchin eggs

Also Known As:

eukaryotic initiation factor-4

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Ribosomal Proteins: 1138
    - Peptide Initiation Factors: 1364
      - eIF-4: 4

Related Diseases

1.	Infections 09/01/1994 - "The primary cleavage products of eIF-4 gamma obtained in vitro with purified leader or 2A proteinase are electrophoretically indistinguishable from those found during infection in vivo. " 11/15/1992 - "The antibodies specifically recognized intact eIF-4 gamma and its cleavage products following poliovirus infection. " 09/01/1994 - "Specific proteolysis of protein synthesis initiation factor eIF-4 gamma occurs during infection with rhinoviruses, enteroviruses, and aphthoviruses, apparently leading to an inability of the ribosomes to bind capped mRNAs. "
2.	Picornaviridae Infections 03/20/1995 - "One member of the group, eIF-4 gamma, is the target for proteolytic cleavage during picornavirus infection, an event that is thought to be responsible for the inhibition of host cellular mRNA translation. "
3.	Pain (Aches) 12/01/1995 - "Previously we have shown that activation of these quiescent cells with either phorbol ester or concanavalin A leads to a rapid increase in the rate of protein synthesis and phosphate-labelling of initiation factor eIF-4 alpha [Morley, Rau, Kay and Pain (1993) Eur. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Peptide Initiation Factors (Initiation Factor)
3.	Phosphates (Orthophosphate)
4.	Phorbol Esters
5.	Peptide Hydrolases (Proteases)
6.	Concanavalin A
7.	Antibodies