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2-N-carboxamidinonormianserin
structure given in first source
Also Known As:
2-carboxamidino-1,2,3,4,10,14b-hexahydrodibenzo(c.f.)pyranzino(1,2-a)azepine hydrochloride; FCC5; Dibenzo(c,f)pyrazino(1,2-a)azepine-2(1H)-carboximidamide, 3,4,10,14b-tetrahydro-, monohydrochloride
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Dibenzazepines: 4
Mianserin: 369
2-N-carboxamidinonormianserin: 2
Related Diseases
1.
Hypersensitivity (Allergy)
02/01/1995 - "
The aims of these studies were to examine the effects of FCC5 (2-carboxamidino-1,2,3,4,10,14b-hexahydrodibenzo (c,f) pyrazino (1,2,-a) azepine HCl), an analogue of mianserin, on immediate type hypersensitivity reactions in-vitro.
"
2.
Tachycardia (Tachyarrhythmias)
10/01/1992 - "
In anaesthetized cats and rats and also pithed rats, FCC5 (0.1-1.0 mg kg-1, i.v.) caused sympathomimetic effects as demonstrated by pressor responses and tachycardia.
"
3.
Otitis
02/01/1995 - "
FCC5 (50 micrograms topically) resembled mianserin and indomethacin in attenuating PMA-induced mouse ear inflammation.
"
4.
Bradycardia
10/01/1992 - "
Higher doses of FCC5 (3 mg kg-1, i.v.) reduced bradycardia and depressor responses to 5-HT in anaesthetized rats.
"
Related Drugs and Biologics
1.
Mianserin
2.
Sympathomimetics (Sympathomimetic Amines)
3.
Serotonin (5 Hydroxytryptamine)
4.
Indomethacin (Indometacin)