cefluprenam

has broad antibacterial spectrum; structure given in first source

Also Known As:

7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-fluoromethoxyiminoacetoamido)-3-(3-carbamoylmethylethylmethylammonio-1-propenyl)-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylate; E 1077; E-1077; E1077

Networked: 6 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - beta-Lactams: 2386
      - Cephalosporins: 4007
        cefluprenam: 6
- Sulfur Compounds: 278
  - Thiazines: 3
    - Cephalosporins: 4007
      - cefluprenam: 6
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - beta-Lactams: 2386
      - Cephalosporins: 4007
        cefluprenam: 6

Related Diseases

1.	Pyometra 02/01/1997 - "We evaluated the efficacy of cefluprenam (CFLP) using a polymicrobial pyometra of a model rat. " 02/01/1997 - "Therapeutic effects of cefluprenam (CFLP) on polymicrobial infections associated with Enterococcus faecalis in rat pyometra model."
2.	Sepsis (Septicemia) 01/01/1993 - "The broad antibacterial spectrum of E1077 was reflected by its in vivo efficacy against experimental septicemia caused by gram-positive and gram-negative bacteria. "
3.	Infections 09/01/1992 - "E1077 showed a protective effect against systemic infections by gram-positive or gram-negative bacteria, as reflected by its in vitro activity. " 07/01/1997 - "Evaluation of efficacy and safety of cefluprenam (code number: E1077, abbreviation: CFLP), a newly developed injectable cephem antibiotics was conducted on adult patients with various infections, and followed by the study group organized from 39 institutions in pediatric field, as the drug showed no toxicity problems in suckling animals. "
4.	Coinfection 02/01/1997 - "Therapeutic effects of cefluprenam (CFLP) on polymicrobial infections associated with Enterococcus faecalis in rat pyometra model."
5.	Urolithiasis 04/01/1998 - "[Therapeutic effect of cefluprenam on polymicrobial urinary tract infection associated with Enterococcus faecalis, using the infectious urolithiasis model in rats]."

Related Drugs and Biologics

1.	cefluprenam
2.	Anti-Bacterial Agents (Antibiotics)
3.	Therapeutic Uses
4.	Cephalosporins (Cephalosporin Antibiotics)
5.	Ceftazidime (Fortum)

Related Therapies and Procedures

1.	Injections
2.	Therapeutics