islet 64k antigen

antibodies to glutamic acid decarboxylase and tryptic fragments of islet 64k antigen are distinct markers for development of insulin-dependent diabetes mellitus

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Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/01/1992 - "Antibodies to GAD and tryptic fragments of islet 64K antigen as distinct markers for development of IDDM. " 10/01/1993 - "The 64,000-M(r) (64K) islet autoantigen, which is considered to be a target protein of beta cell destruction in insulin-dependent diabetes mellitus (IDDM), has recently been identified as the enzyme glutamic acid decarboxylase (GAD). "
2.	Infections 01/01/1993 - "Congenic B10.BR/SgSnJ H-2kTlaa mice were infected with a diabetogenic strain of coxsackievirus CB4 to correlate abnormalities of sugar metabolism with virus replication in islets, 64,000-M(r) (64K) islet autoantigen expression, 64K antibody development, and pancreas histopathology in early and late infection. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Glutamate Decarboxylase (Decarboxylase, Glutamate)
3.	Enzymes
4.	Antibodies
5.	Sugars