quinotolast

an anti-allergy agent; FR 71021 is the monosodium salt

Also Known As:

FR 71021; FR-71021; FR71021; quinotolast sodium; quinotolast sodium, monohydrate; quinotolast sodium, tetrahydrate; sodium 5-(4-oxo-1-phenoxy-4H-quinolizine-3-carboxamide)tetrazolate

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Tetrazoles: 14
      - quinotolast: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolizines: 1
      - quinotolast: 1

Related Diseases

Hypersensitivity (Allergy)

09/01/1993 - "The results suggest that quinotolast will be beneficial in the treatment of type I allergy-related diseases."
09/01/1993 - "Thus, the effect of quinotolast on type I allergic reaction would seem to be based on an inhibition of mediator release from inflammatory cells including mast cells. "
09/01/1993 - "Quinotolast potently inhibited such type I allergic reactions as passive cutaneous anaphylaxis (PCA) and anaphylactic bronchoconstriction in rats by both intravenous and oral dosing. "