encoded by the crmA gene (cytokine response modifier gene); prevents the proteolytic activation of IL-1, thereby suppressing an IL-1beta response to infection; amino acid sequence has been determined; cytokine response modifier A a strategically deployed viral weapon
Also Known As:
Crma protein; Crma protein, Cowpox virus; ICE-I protein; IL-1-CEI; IL-1beta converting enzyme inhibitor; SPI-2 cysteine proteinase inhibitor; SPI-2 protein, Cowpox virus; Serp-2 protein, Cowpox virus; caspase-1 inhibitor; cytokine response modifier protein, Cowpox virus; hemorrhage-inducing 38 kDa protein, Cowpox virus; serine proteinase inhibitor 2 protein, Cowpox virus