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9- (1'- hydroxy- 2'- (hydroxymethyl)ethoxy)methylguanine

structure given in first source

Also Known As:

9-MG

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Hypoxanthines: 1
        Guanine: 1793
        9-(1'-hydroxy-2'-(hydroxymethyl)ethoxy)methylguanine: 5

Experts

1.	Beebe, Dean W: 1 article (05/2015)
2.	Byars, Anna W: 1 article (05/2015)
3.	Glauser, Tracy A: 1 article (05/2015)
4.	Holland, Katherine: 1 article (05/2015)
5.	Horn, Paul S: 1 article (05/2015)
6.	Jain, Sejal V: 1 article (05/2015)
7.	Simakajornboon, Narong: 1 article (05/2015)
8.	Cheng, J B: 1 article (06/2011)
9.	Colman, P: 1 article (06/2011)
10.	Corey, T P: 1 article (06/2011)

Related Diseases

1.	Hypotension (Low Blood Pressure) 06/01/2011 - "Two subjects who had received 9-mg doses experienced serious adverse events (SAEs), characterized by flu-like symptoms, hypotension, and lymphopenia, leading to early termination of the study. " 01/01/2023 - "The participants received prophylactic epinephrine infusions at rates of 0.01, 0.02, or 0.03 mcg/kg/min. Spinal hypotension (systolic blood pressure <80% of baseline) was managed with a 9-mg ephedrine bolus. "
2.	Lymphopenia (Lymphocytopenia) 06/01/2011 - "Two subjects who had received 9-mg doses experienced serious adverse events (SAEs), characterized by flu-like symptoms, hypotension, and lymphopenia, leading to early termination of the study. "
3.	Pruritus (Itching) 08/01/2000 - "Pruritus decreased significantly more in the prednisone group compared to both the 3-mg and the 9-mg budesonide groups (p < 0.05). "
4.	Epilepsy (Aura) 05/01/2015 - "Eleven prepubertal, developmentally normal children aged 6-11 years with epilepsy were randomized by a software algorithm to receive placebo or a 9-mg sustained release (SR) melatonin formulation for four weeks, followed by a one-week washout and a four-week crossover condition. "
5.	Edema (Dropsy) 12/01/1999 - "A single topical application of silymarin at 3-, 6-, and 9-mg doses onto SENCAR mouse skin followed 30 min later with 12-O-tetradecanoylphorbol 13-acetate (TPA) at a 3-microg dose resulted in a 76-95% inhibition (P < 0.001) of TPA-caused skin edema. "

Related Drugs and Biologics

1.	Budesonide (Pulmicort)
2.	Silymarin
3.	Prednisone (Sone)
4.	Melatonin
5.	Epinephrine (Adrenaline)
6.	Ephedrine