LVV-hemorphin-7

a morphinomimetic peptide; amino acid sequence given in first source; isolated from ventricular cerebrospinal fluid of patients with cerebrovascular bleedings

Also Known As:

LVV-H7; Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe; leucyl-valyl-valyl-tyrosyl-prolyl-tryptophyl-threonyl-glutaminyl-arginyl-phenylalanine

Networked: 12 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - LVV-hemorphin-7: 12
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        LVV-hemorphin-7: 12
- Peptides: 82426
  - Peptide Fragments: 373
    - LVV-hemorphin-7: 12

Experts

1.	Huang, Eagle Yi-Kung: 3 articles (01/2021 - 07/2012)
2.	Chen, Yuan-Hao: 2 articles (01/2021 - 10/2016)
3.	Chow, Lok-Hi: 2 articles (01/2021 - 10/2016)
4.	Chang, Jung-Su: 1 article (11/2021)
5.	Chen, Seu-Hwa: 1 article (11/2021)
6.	Chuang, Yung-Kun: 1 article (11/2021)
7.	Faradina, Amelia: 1 article (11/2021)
8.	Huang, Shih-Yi: 1 article (11/2021)
9.	Lee, Yu-Chieh: 1 article (11/2021)
10.	Skalny, Anatoly V: 1 article (11/2021)

Related Diseases

1.	Pain (Aches) 01/01/2021 - "Using different pharmacological strategies to affect the LVV-H7 level, we investigated the correlation between LVV-H7 and pain-related behavior. " 01/01/2021 - "LVV-hemorphin-7 (LVV-H7) plays a role in antinociception in a rat model of alcohol-induced pain disorders." 01/01/2021 - "This study may help to develop LVV-H7 structure-based novel analgesics for treating alcohol-induced pain disorders and thus ameliorate the complications in alcoholics." 01/01/2021 - "We hypothesized that chronic alcohol consumption changes the level of LVV-hemorphin-7 (abbreviated as LVV-H7, an opioid-like peptide generated from hemoglobin β-chain), thereby affecting pain sensation. "
2.	Memory Disorders (Memory Loss) 10/14/2019 - "Thus, camel LVV-hemorphin-7 could be explored as a potent therapeutic agent for memory loss, hypertension, and analgesia."
3.	Hypertension (High Blood Pressure) 10/14/2019 - "Thus, camel LVV-hemorphin-7 could be explored as a potent therapeutic agent for memory loss, hypertension, and analgesia."
4.	Tachycardia (Tachyarrhythmias) 01/01/1998 - "Drug interaction studies using various inhibitory drugs (e.g., phentolamine, clonidine, etc.) and LVV-H7 showed that the pressor effect and tachycardia elicited by LVV-H7 involved the activation of the sympathetic nervous system (SNS). " 01/01/1998 - "The pressor effect and tachycardia caused by LVV-H7 were potentiated by captopril, suggesting that the angiotensin converting enzyme may contribute to the inactivation of LVV-H7 in rats. "
5.	Neuroblastoma 03/01/2001 - "In summary, the human neuroblastoma cell line, SK-N-MC, expresses functional AT(4) receptors that are responsive to Ang IV and LVV-H7, as indicated by an increase in DNA synthesis. " 07/01/1999 - "In the neuroblastoma/glioma hybrid cell line, NG108-15, LVV-hemorphin-7 and angiotensin IV competed for 125I-angiotensin IV binding in a biphasic fashion with IC50 values of 1.2 x 10(-10) and 1.1 x 10(-9) M for the high-affinity site, respectively, and 6.7 x 10(-8) and 1.5 x 10(-8) M for the low-affinity site, respectively. "

Related Drugs and Biologics

1.	Analgesics (Analgesic Drugs)
2.	Phentolamine (Z-Max)
3.	Clonidine (ST 155)
4.	Hemoglobins (Hemoglobin)
5.	Peptides (Polypeptides)
6.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
7.	Insulin (Novolin)
8.	Opioid Peptides (Opioid Peptide)
9.	Biomarkers (Surrogate Marker)
10.	Growth Hormone (Somatotropin)

Related Therapies and Procedures

1.	Analgesia