estradiol 3-benzoate (estradiol benzoate)

09/01/1983 - "Two days after a single injection of estradiol benzoate (100 micrograms/kg body wt) in ovariectomized rats, a significantly greater number (7.8 +/- 0.2) of lordosis responses could be elicited before the response was exhausted (P less than 0.01). "
09/01/2015 - "The acute administration of estradiol benzoate (EB) to the ovariectomized (OVX) rat induces low levels of lordosis while sexually appetitive behaviors (e.g., hops, darts, solicitations) are absent, yet the repeated administration of EB results in a behavioral sensitization in which lordosis is potentiated and sexually appetitive behaviors are induced. "
09/01/2014 - "In female rats sexual receptivity (lordosis) can be induced with either a single large dose of estradiol benzoate (EB), or a priming dose of EB that does not induce sexual receptivity followed by 17β-estradiol (E2). "
07/01/2014 - "A brief restraint experience reduces lordosis behavior in ovariectomized females that have been hormonally primed with estradiol benzoate. "
02/01/2014 - "Rats without prior hormonal priming showed a decline in lordosis behavior after restraint but prior priming with estradiol benzoate reduced this effect. "

12/01/1976 - "In the first study, it was found that concentrations of estradiol benzoate effective in suppressing food intake and body weight in nonlactating animals were not effective during lactation. "
08/01/1989 - "In the present study the effect of estradiol benzoate (EB) treatment (50 micrograms/kg body weight/2 days) on [3H]-OT binding was evaluated in adult and 21-day-old gonadectomized male and female rat brains. "
09/01/1976 - "In a second study, ovx rats were primed with 5 mug estradiol benzoate/100 g body weight/day for 2 days prior to stimulation. "
10/01/2008 - "Adult female Wistar rats (n = 21) were ovariectomized and received one week later a single dose of estradiol benzoate (1.5 mg/kg body weight, i.m. "
06/10/2001 - "beta-estradiol 3-benzoate (E(2)B) (10, 16, 20, 40, 80 and 160 microg/kg body weight) was administered daily to experimental groups of adult mice for the following periods; 2, 3 days, 1, 2, 4, and 8 weeks. "

01/01/1989 - "In contrary, the pronounced stimulation of tumor growth (% T/C = 152) by estradiol benzoate (EB, 0.33 microgram/mouse, 3 times weekly, s.c.) was completely inhibited (% T/C = 7) by the antiprogesterones. "
07/01/1979 - "In the control and estradiol benzoate-treated postpartum lactating rats, the mammary tumors decreased approximately 40% in size by Day 5 postpartum and continued to regress to 50% of their average original diameter by Day 25 postpartum. "
08/01/1953 - "Uteri (human) cancer free following two to ten years of weekly large doses of estradiol benzoate."
07/01/1979 - "The effects of bilateral adrenalectomy or estradiol benzoate treatment were observed on growth of 7,12-dimethylbenz(a)-anthracene-induced mammary tumors during postpartum lactation. "
09/01/1976 - "Injections of 10 or 25 mug estradiol benzoate daily for 10 days effectively inhibited mammary tumor growth and significantly reduced specific PRL binding to mammary tumor cell membranes."

08/01/1993 - "Ovariectomized rats pretreated with estradiol benzoate (EB) exhibited significantly greater catalepsy than did females untreated or treated with progesterone or combined EB and progesterone. "
11/21/1983 - "Repeated administration with estradiol benzoate (5 micrograms/rat, twice daily for 10 days) significantly potentiated catalepsy induced by 0.25 or 0.5 mg/kg haloperidol, but no effect was observed 10 min or 1 h after a single injection of estradiol benzoate (5 or 50 micrograms/rat). "
01/31/1983 - "It was found that 7-days estradiol benzoate treatment (5 micrograms/rat/day) significantly increases haloperidol-induced catalepsy, suggesting a possible antidopaminergic activity of estrogens. "

12/01/1988 - "We have used estradiol benzoate (E) and Progesterone (P) for the treatment of severe pre-eclampsia and obtained good results in 8 cases. "