Human herpesvirus 3 IE62 protein

IE62 may be a good immune stimulus because it is a large (MW 140-170 kDa) protein that contains multiple short amino acid sequences recognizable by T lymphocytes; expressed abundantly in infected cells; shares functional similarities with ICP4 of HSV-1; amino acid sequence known

Also Known As:

IE62 protein, Human herpesvirus 3; IE62 protein, VZV; ORF62 protein, VZV; VZV ORF62; immediate early protein 62, Varicella-zoster virus; protein 62, Varicella-zoster virus; varicella-zoster virus IE62

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Anholts, J D H: 1 article (08/2017)
2.	Claas, F H J: 1 article (08/2017)
3.	Franke-van Dijk, M E I: 1 article (08/2017)
4.	Heutinck, K M: 1 article (08/2017)
5.	Roelen, D L: 1 article (08/2017)
6.	Ten Berge, R J M: 1 article (08/2017)
7.	Yong, S L: 1 article (08/2017)
8.	Zhang, X Q: 1 article (08/2017)
9.	van Miert, P P M C: 1 article (08/2017)
10.	van den Heuvel, H: 1 article (08/2017)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 04/01/1994 - "To investigate whether these proteins function during the initial stages of VZV infection, human melanoma cells were cotransfected with purified VZV DNA, devoid of any structural proteins, along with a plasmid expressing VZV ORF62 or ORF10 under the control of the human cytomegalovirus major immediate-early promoter. "
2.	Human Influenza (Influenza) 08/01/2017 - "CMV B35/IPS CD8+ T cells cross-reacted with HLA-B51 and/or HLA-B58/B57 (23% of tetramer-positive individuals), FLU A2/GIL (influenza IMP[58-66] HLA-A02:01/GILGFVFTL) CD8+ T cells with HLA-B38 (90% of tetramer-positive individuals), and VZV A2/ALW (varicella zoster virus IE62[593-601] HLA-A02:01/ALWALPHAA) CD8+ T cells with HLA-B55 (two unrelated individuals). "
3.	Infections 04/01/1994 - "To investigate whether these proteins function during the initial stages of VZV infection, human melanoma cells were cotransfected with purified VZV DNA, devoid of any structural proteins, along with a plasmid expressing VZV ORF62 or ORF10 under the control of the human cytomegalovirus major immediate-early promoter. "
4.	Chickenpox 11/01/1993 - "DNA sequence of a simian varicella virus gene that encodes a homologue of varicella zoster virus IE62 and herpes simplex virus ICP4."

Related Drugs and Biologics

1.	HLA-B51 Antigen
2.	HLA-B38 Antigen
3.	HLA-A Antigens (HLA-A)
4.	Proteins (Proteins, Gene)
5.	Inosine Monophosphate (IMP)
6.	DNA (Deoxyribonucleic Acid)
7.	influenza matrix peptide (58-66)
8.	HLA-B55 antigen