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chlorophenol red galactopyranoside (CPRG)

a chromogenic substrate used for detection of beta-galactosidase in transfected mammalian cells

Also Known As:

CPRG; chlorophenol red beta-D-galactopyranoside

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Chlorophenols: 95
        chlorophenol red galactopyranoside: 4
        Chlorobenzenes: 5
        Chlorophenols: 95
        chlorophenol red galactopyranoside: 4
Carbohydrates: 22023
- Glycosides: 2119
  - Galactosides: 43
    - chlorophenol red galactopyranoside: 4

Experts

1.	Hirata, Yuki: 1 article (04/2014)
2.	Mochizuki, Tomofumi: 1 article (04/2014)
3.	Ogata, Yoshiyuki: 1 article (04/2014)
4.	Ohki, Satoshi T: 1 article (04/2014)
5.	Nanavaty, Mayank A: 1 article (12/2005)
6.	Raj, Shetal M: 1 article (12/2005)
7.	Vasavada, Abhay R: 1 article (12/2005)
8.	Buller, C J: 1 article (11/2003)
9.	Howard, E W: 1 article (11/2003)
10.	Pento, J T: 1 article (11/2003)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2002 - "In addition, 31P-NMR studies on the xenografted tumor revealed that cPrG x HCl lowered tumor pHi (below pH 6.9). " 11/01/2003 - "We concluded that the CPRG substrate-based assay represents a reliable technique for the determination of beta-gal activity in transfected cancer cells present in tumor and tissue specimens from the nude mouse xenograft model." 03/01/2002 - "The TUNEL staining revealed that tumor cells in cPrG x HCl plus epirubicin-treated mice exhibited a higher apoptotic rate. " 03/01/2002 - "Either cPrG x HCl or epirubicin alone showed a tumor growth inhibition in a time- and dose-dependent manner, however, the combinatory use of cPrG x HCl together with epirubicin resulted in prominent synergistic effects on the breast cancer cells. "
2.	Cataract (Cataracts) 12/01/2005 - "A prospective controlled randomized double-masked analysis of 30 consecutive patients with CPRG defect and bilateral cataracts received a Natural IOL (test group) in 1 eye and a single-piece AcrySof IOL (control group) in the other eye. "
3.	Breast Neoplasms (Breast Cancer) 03/01/2002 - "The effects of cPrG x HCl and epirubicin on the suppression of cell growth were examined on human breast cancer cell line (MDA-MB-231). " 03/01/2002 - "These results suggest that the combinatory use of cPrG x HCl and epirubicin may be useful for breast cancer therapy." 03/01/2002 - "Either cPrG x HCl or epirubicin alone showed a tumor growth inhibition in a time- and dose-dependent manner, however, the combinatory use of cPrG x HCl together with epirubicin resulted in prominent synergistic effects on the breast cancer cells. "
4.	Hypochromic Anemia (Chlorosis) 04/01/2014 - "Interestingly, the level of CPRG down-regulation was correlated with the severity of chlorosis. "

Related Drugs and Biologics

1.	Epirubicin (Ellence)

Related Therapies and Procedures

1.	Therapeutics