systemin

amino acid sequence given in first source; a mobile 18 amino acid polypeptide, induces proteinase inhibitor synthesis; from Lycopersicon esculentum (tomato)

Also Known As:

L-aspartic acid, L-alanyl-L-valyl-L-glutaminyl-L-seryl-L-lysyl-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-arginyl-L-alpha-aspartyl-L-prolyl-L-prolyl-L-lysyl-L-methionyl-L-glutaminyl-L-threonyl-

Networked: 68 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - systemin: 68

Experts

1.	Stratmann, Johannes W: 6 articles (01/2010 - 08/2002)
2.	Li, Chuanyou: 4 articles (01/2013 - 04/2002)
3.	Howe, Gregg A: 4 articles (07/2007 - 04/2002)
4.	Baldwin, Ian T: 3 articles (03/2009 - 07/2006)
5.	Ryan, Clarence A: 3 articles (12/2007 - 08/2003)
6.	Lee, Gyu In: 3 articles (07/2003 - 04/2002)
7.	Rao, Rosa: 2 articles (12/2020 - 01/2010)
8.	Schaller, Andreas: 2 articles (01/2019 - 01/2018)
9.	Stintzi, Annick: 2 articles (01/2019 - 01/2018)
10.	Sun, Jiaqiang: 2 articles (01/2013 - 05/2006)

Related Diseases

1.	Wounds and Injuries (Trauma) 11/01/1999 - "To study further the role of (pro)systemin in the wound response pathway, we isolated and characterized mutations that suppress 35S::prosys-mediated phenotypes. " 03/01/2009 - "After simulated herbivory, inflicted by a treatment involving wounding and the application of Manduca sexta oral secretions (OS) to mechanical wounds (OS-elicitation), transcripts of the systemin-precursor, prosystemin, are down-regulated in black nightshade (Solanum nigrum). " 01/01/2008 - "Overall the data indicates that mutants defective in tomato BRI1 are not defective in systemin-induced wound signalling and that systemin perception can occur via a non-BRI1 mechanism." 01/01/2008 - "The role of tomato BRI1 in BR signalling was confirmed, however it was found not to be essential for systemin/wound signalling. " 01/01/2008 - "Tomato BRI1 and systemin wound signalling."
2.	Infections 08/01/2022 - "Using transcriptional and metabolomics approaches, and loss-of-function mutants to analyse the molecular mechanisms underlying induced resistance against the necrotroph, we decipher the enhanced molecular responses in Systemin-treated plants following infection. " 01/01/2020 - "Additionally, Systemin treated plants display enhanced BAK1 and BIK1 gene expression following infection as well as increased production of ROS after PAMP treatment suggesting that Systemin sensitizes Arabidopsis perception to pathogens and PAMPs." 01/01/2018 - "Systemin, a peptide specific to the Solanaceae, is known for its functions in plant responses to insect herbivory and pathogen infections. " 08/01/2022 - "Some protein complexes involved in the response to other damage signals, including the BAK1-BIK1 protein complex and heterotrimeric G proteins, as well as MPK activation, were among the early signalling events triggered by Systemin in Arabidopsis upon infection. "
3.	Disease Resistance 07/01/2007 - "The results indicated that the pattern of systemic disease resistance conferred by mycorrhizal colonization was dependent on the AMF employed and could be altered by the exogenous application of systemin, by means of a still undefined mechanism." 07/01/2007 - "Exogenous systemin has a contrasting effect on disease resistance in mycorrhizal tomato (Solanum lycopersicum) plants infected with necrotrophic or hemibiotrophic pathogens."
4.	Tetraploidy 07/01/2006 - "attenuata pro-systemin construct confirmed the genotype dependency of tetraploidization: none of the 23 transgenic Utah lines were tetraploid but 31 (72%) of 43 transgenic Arizonas were tetraploid. "
5.	Neoplasms (Cancer) 01/01/2021 - "Emerging clinical evidences suggest that the presentation of tumor neoantigens and neoantigen-specific T cell response associated with MHC class I molecules are of key importance to activate the adaptive immune systemin cancer immunotherapy. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Peptides (Polypeptides)
3.	jasmonic acid (jasmonate)
4.	Peptide Hydrolases (Proteases)
5.	Acids
6.	Plant Growth Regulators (Plant Hormones)
7.	Phosphotransferases (Kinase)
8.	Suspensions
9.	Hormones (Hormone)
10.	Brassinosteroids

Related Therapies and Procedures

1.	Antibiotic Prophylaxis
2.	Immunotherapy