heat shock transcription factor (heat shock transcription factors)

12/01/1991 - "This possibility we tested on three levels: protection against heat (thermotolerance), induction of specific HSP, and binding of the heat shock transcription factor to the heat shock element. "
02/03/2006 - "Studies have indicated the role of HSF1 (heat-shock transcription factor 1) in repressing the transcription of some nonheat shock genes. "
05/01/2014 - "In all animals the regulatory regions of studied heat shock genes include several conservative promoter elements HSEs (heat shock elements) that are necessary for binding of heat shock transcription factor (HSF). "
12/01/2013 - "There was also little overlap with genes that are activated or repressed during heat-shock, with only 5% of them regulated by the heat-shock transcription factor. "
05/01/2013 - "It is known that, in vitro, promoter architecture (the order and spacing of these repeats) impacts the interaction of various heat shock transcription factors (HSFs) with the heat shock promoter, but in vivo relevance of these binding preferences so far as the expression is concerned is poorly understood. "

01/01/2012 - "Our previous study showed that heat shock transcription factor 1 (HSF1) overexpression could increase the anti-tumor efficacy of E1B55kD deleted oncolytic adenovirus through increasing the viral burst. "
02/01/2015 - "Heat shock transcription factor 1 (HSF1), the major regulator of stress response, is frequently activated in cancer and has an apparent role in malignant transformation. "
09/16/2010 - "The heat-shock transcription factor HSF1 was recently shown to have a key role in the development of tumors associated with activation of Ras or inactivation of p53. "
04/07/2006 - "In transformed cells and tumors, chaperones are frequently overexpressed, with constitutive activation of the heat shock transcription factor HSF1 implicated in tumor formation. "
07/01/2004 - "We show that activation of the stress response within tumor cells during cell death, using an engineered form of the heat shock transcription factor, leads to an immunogenic death. "

05/01/1992 - "Molecular signals for the activation of heat shock transcription factor during ischemia."
08/01/1996 - "We further find that, contrary to some earlier reports, simulated ischemia activates the heat shock transcription factor (HSF) rapidly, as is the case for heat shock."
11/01/1996 - "We examined the DNA-binding activity of heat shock transcription factor (HSF), by which the transcription of heat shock genes is mainly regulated, during heat shock or ischemia/reperfusion in isolated rat heart. "
10/01/2006 - "In this study, we examined insulin- and heat shock-treated hearts for improved contractile recovery after 30 min of ischemia, activation of the heat shock transcription factor, and localization of the Hsp70 in relation to dystrophin and alpha-tubulin. "

11/01/2011 - "Heat shock transcription factor 1 (HSF1) plays an important role not only in excise-induced cardiac hypertrophy but also in protection against pressure overload-induced cardiac dysfunction. "
02/16/2007 - "Adaptive and maladaptive cardiac hypertrophy: what is the effective role of heat shock transcription factor 1?"
12/08/2006 - "Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy."
04/01/2008 - "By comparing the two types of cardiac hypertrophy, we have identified heat shock transcription factor 1 and its target heat shock proteins as key factors involved in the adaptive mechanism of cardiac hypertrophy. "
12/08/2006 - "Here, we showed a critical role of heat shock transcription factor 1 (HSF1), an important transcription factor for heat shock proteins, in the adaptive mechanism of cardiac hypertrophy. "

04/05/2002 - "Heat shock factor (HSF) 1 is the major heat shock transcription factor that regulates stress-inducible synthesis of heat shock proteins and is also essential in protection against endotoxic shock. "