usnic acid

06/01/2019 - "Bioadhesive polymeric films based on usnic acid for burn wound treatment: Antibacterial and cytotoxicity studies."
01/01/2011 - "It was concluded that the use of reconstituted bovine type-I collagen-based films containing usnic acid improved burn healing process in rats."
06/01/2019 - "Usnic acid (UA) is a lichenic secondary metabolite useful for the treatment of burn wounds thanks to its antimicrobial activity, particularly toward strains responsible for their infections. "
01/01/2011 - "The aim of this study was assess the effect of collagen-based films containing usnic acid as a wound dressing for dermal burn healing. "
07/03/2023 - "As these structures also allow the incorporation of bioactive agents due to their high surface-area-to-volume ratio, the interesting point was to incorporate usnic acid into the structure as it is a natural and suitable alternative agent for burn wounds treatment which avoids an improper or overuse of antibiotics and other invasive biomolecules. "

08/01/2009 - "Rat cardiac fibroblasts incubated with (+)-usnic acid showed obvious growth inhibition, which was positively correlated to the dose of (+)-usnic acid, and high dose of (+)-usnic acid caused severe cell injuries. "
06/01/2019 - "Bioadhesive polymeric films based on usnic acid for burn wound treatment: Antibacterial and cytotoxicity studies."
09/01/2020 - "Our findings indicate that usnic acid has neuroprotective properties, which possibly is applicable as a promising candidate for cerebral injuries caused by ischemia."
01/01/2021 - "Usnic-Acid-Functionalized Silk Fibroin Composite Scaffolds for Cutaneous Wounds Healing."
01/01/2018 - "In conclusion, our results indicate that the topical use of sodium usnic acid could promote skin wound healing, and this mechanism might be related to anti-inflammatory effects at the wound site."

02/12/2023 - "Effects of Usnic Acid to Prevent Infections by Creating a Protective Barrier in an In Vitro Study."
01/01/2015 - "Derivatives of usnic acid inhibit broad range of influenza viruses and protect mice from lethal influenza infection."
01/01/2020 - "Therefore, it was possible to observe that usnic acid is a promising candidate to be used in combination with polymyxin B against infections caused by resistant P. "
12/15/2019 - "uncialis acetone extract (CUE) and usnic acid (UA) enantiomers against ten clinical microbial strains causing skin infections. "
11/01/2018 - "New drugs are needed to treat infections with antimicrobial-resistant Mycobacterium abscessus; therefore, we evaluated usnic acid as an antimicrobial agent and efflux inhibitor (EI) against M. abscessus. "

10/01/2014 - "In the present study, we found that pretreatment with usnic acid significantly improved survival rate, pulmonary edema. "

01/01/2022 - "We report the in vitro anti-SARS-CoV-2 efficacy of (+)-usnic acid in this study and propose that it has the potential to be developed as a COVID-19 treatment if its in vivo efficacy has been confirmed."