polyethylene oxide-polybutylene terephthalate copolymer

01/01/2015 - "Not only did we find several cases of severe osteolysis in our own study population of 284 patients, several articles have lately described potential harmful side effects of the PolyActive material in humans. "
06/01/2008 - "Deleterious tissue reaction with dramatic signs of osteolysis and inflammatory foreign-body reaction was observed around the Polyactive stems. "

12/01/1999 - "The present study aims at optimizing dermal fibroblast seeding and cultivation in Polyactive scaffolds in order to limit the biopsy size needed for autologous treatment of full-thickness skin defects and chronic wounds. "

06/01/2008 - "In contrary to previous in vivo studies suggesting biocompatibility, osteoconductivity and capability to bond to bone, Polyactive 1000PEO70PBT30 stem in this setting caused massive osteolytic lesions and foreign-body reactions."

08/15/1994 - "This study determined the ability of a Polyactive membrane to prevent perineural scar and compared the results to those obtained using free fat graft and nonimplanted control subjects. "
08/15/1994 - "The results indicate Polyactive is a reliable and effective means of reducing perineural scar formation. "
08/15/1994 - "Polyactive membranes were an effective barrier with only minimal scar formation to the dura observed at any time period. "
08/15/1994 - "The effectiveness of Polyactive (Osteotech, Inc., Shrewsbury, NJ), an elastomeric segmental copolymer, as a barrier material for the prevention of perineural scar formation was evaluated in eight adult mongrel dogs. "
08/15/1994 - "Reduction in perineural scar formation after laminectomy with Polyactive membrane sheets."

09/01/1991 - "Polyactive provoked a mild foreign-body reaction, showed a degradation rate of 54 percent after 1 year, and was nontoxic. "
06/01/2008 - "Deleterious tissue reaction with dramatic signs of osteolysis and inflammatory foreign-body reaction was observed around the Polyactive stems. "