4-borono-2-fluorophenylalanine

used as a target cpd for boron neutron capture therapy; RN given refers to (DL)-isomer 18F-labeled cpd; RN for unlabeled cpd without isomeric designation not avail 3/92

Also Known As:

(18F)-(10B)-L-BPA; 18F-10B-FBPA; 4-BF-Phe; 4-borono-2-(18F)fluoro-DL-phenylalanine; 4-borono-2-fluoro-L-phenylalanine; fluoroboronophenylalanine

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Imahori, Yoshio: 1 article (12/2003)
2.	Mineura, Katsuyoshi: 1 article (12/2003)
3.	Takahashi, Yoshinobu: 1 article (12/2003)

Related Diseases

1.	Neoplasms (Cancer) 08/01/1998 - "Based on pharmacokinetic findings of fluorine-18-labeled L-fluoroboronophenylalanine by positron emission tomography (PET), methods for estimating tumor 10B concentration were devised. " 02/01/1998 - "The accumulation of 18F-10B-FBPA was found to correlate with the degree of malignancy, and the L form of 18F-10B-FBPA was taken up better than was the DL form. " 02/01/1998 - "Dynamic PET images of 18F-10B-FBPA incorporation into tumors were obtained, and the arterial blood samplings were performed in all cases. "
2.	Glioma (Gliomas) 02/01/1998 - "We synthesized fluorine-18-labeled fluoroboronophenylalanine (18F-10B-FBPA), an analog of boronophenylalanine (10B-BPA), and characterized its pharmacokinetics in patients with glioma. " 02/01/1998 - "Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma." 12/01/2003 - "Prognostic and therapeutic indicator of fluoroboronophenylalanine positron emission tomography in patients with gliomas."

Related Drugs and Biologics

1.	Indicators and Reagents (Reagents)