4-hexyloxyaniline (HOA)

11/22/2021 - "In HOA patients, AUSCAN pain improved more in group 1 compared to group 2 at M3, M6 and M12 (p<0.001, p=0.001 and p=0.038, respectively). "
06/01/2020 - "The combination of GS with conventional treatment seems to be more effective in improving pain and function than conventional HOA treatment alone. "
10/01/2023 - "Therefore, the objective of this review was to assess the efficacy of PRP versus HA in terms of pain relief and functional outcomes for the management of HOA. "
07/01/2020 - "Conclusion: The combination of intra-articular and intra-osseous infiltrations of PRP showed a pain reduction and improvement in hip joint functionality up to 12 months in patients with severe HOA, with no severe adverse effects."
01/01/2022 - "The aim of this study was to comprehensively quantify the effects of unilateral HOA as well as functional hip bracing on gait biomechanics, pain, proprioception and functional capacity in people with mild to moderate HOA. "

09/01/2020 - "Three studies described statistically significant reduction in the number of total HOA, in particular, those related to coma and spherical aberration. "
05/24/2023 - "These patients were re-treated using an epi-OFF protocol and after 2 years all patients were stable, and a statistically significant reduction of the mean Kmax (P = .007), HOA RMS (P = .05), and coma RMS (P = 05) was observed. "
03/01/2023 - "Among the anterior HOAs, total HOA, coma, and trefoil showed significant improvement after surgery ( P = 0.003, P = 0.009, and P = 0.018, respectively). "
02/01/2023 - "The 10-minute protocol had significantly improved outcomes compared with the 5-minute protocol for the mean changes in K1 and K2 ( P < 0.00001), corneal total HOA ( P = 0.0002), and corneal coma ( P = 0.00001). "
07/01/2020 - "Total anterior corneal HOA, vertical coma, and horizontal coma anterior corneal HOAs significantly improved by -1.05 ± 0.93 μm (P < .001), -1.53 ± 1.18 μm (P < .001), and -0.35 ± 0.57 μm (P < .001), respectively. "

07/01/2021 - "A variety of exercise programs are recognized to be effective for the management of hand osteoarthritis (HOA). "
11/26/2021 - "This study aims to render this analysis easier in order to enable the applicability of the early detection of hand osteoarthritis (HOA) and the identification of indicators of dysfunction. "
01/01/2021 - "The objective of this study was to verify whether women in the initial stages of hand osteoarthritis (HOA) already have impaired grip strength and flexor and extensor torque of the wrist compared to healthy women. "
01/01/2021 - "This study measured the magnitude and determinants of clinical and radiological progression in patients with hand osteoarthritis (HOA) over a 2-year prospective follow-up to gain a greater understanding of the disease time course. "
01/01/2021 - "However, it is unknown if the clinical signs of hand osteoarthritis (HOA) cause impairment in the activation of these muscles PURPOSE OF THE STUDY: The purpose of this study was to investigate whether early-stage HOA affects the magnitude of activation and coactivation between the wrist extensor and flexor muscles METHODS: Thirty-two subjects were divided into two groups: control group (n = 16; 55 ± 7.42 years) and a group with HOA grades 2 or 3 (HOAG; n = 16; 57 ± 7.82 years). "

04/10/2021 - "Both of two techniques were safe and effective for myopia and compared to Artisan PIOL, Artiflex PIOL had significant improvement in efficacy, predictability, contrast sensitivityand HOA, except safety and complications in the treatment of moderate to high myopia."
02/01/2020 - "The overall WMD showed statistical significance in terms of postoperative uncorrected distance visual acuity (UDVA), mean postoperative spherical equivalence (SE), and mean postoperative intraocular higher-order aberrations (HOA) (μm) for a 6-mm pupil, suggesting that foldable PIOL group showed significant improvement of high myopia, compared to rigid PIOL group. "
09/01/2007 - "The findings suggest that individualized aspheric keratoablation is effective in patients with mild and moderate myopia with varying baseline HOA. "
12/01/2018 - "Peripheral higher order aberrations (HOA) of 646 children at 30° temporal, nasal and inferior visual field were measured under cycloplegia (5 mm pupil diameter) using a commercially available Shack-Hartmann aberrometer in the Sydney Myopia Study [age, 12.7 ± 0.4 years (mean ± standard deviation)] and five years later in the Sydney Adolescent Vascular and Eye Study. "
02/01/2023 - "Stratified analyses showed that the AOK group exhibited greater HOA and SA at 5-mm and 6-mm pupil diameters in the lower myopia subgroup and greater SA at 6 mm in the higher myopia subgroup (all P<0.05). "

01/01/2022 - "In contrast to knee osteoarthritis, little is known about the effectiveness of hip bracing for the management of HOA. "
11/22/2021 - "The primary objective of this study was to assess the efficacy of mud plus bath therapy in comparison to bath therapy alone in hand and knee osteoarthritis (HOA and KOA). "
09/01/2012 - "Diagnostic and procedural codes were used to determine the incidence of hip and knee osteoarthritis (HOA and KOA) and of THA and total knee arthroplasty (TKA) among the cases and controls and their relatives. "
12/31/2022 - "This study conducted a Mendelian Randomization (MR) analysis for the causal effects of general adiposity and abdominal adiposity on knee osteoarthritis (KOA) and hip osteoarthritis (HOA). "
10/30/2019 - "The objective of this study was to obtain utilities by means of EQ-5D-5L for different health states in patients with knee osteoarthritis (KOA) or hip osteoarthritis (HOA) in Spain, and to compare these values with those used in foreign studies with the aim of discussing their transferability for their use in economic evaluations conducted in Spain. "