BN 52205

a synthetic aza alkyl lysophospholipid of MW 436; structure given in first source

Also Known As:

3-methoxy-2-N,N-methyloctadecylaminopropyloxyphosphorylcholine; BN-52205; 3,5-Dioxa-8-aza-4-phosphahexacosan-1-aminium, 4-hydroxy-7-(methoxymethyl)-N,N,N,8-tetramethyl-, hydroxide, inner salt, 4-oxide

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Lysophospholipids: 554
        BN 52205: 3

Related Diseases

1.	Neoplasms (Cancer) 01/01/1994 - "The study of the degree of differential growth inhibition has shown a statistically significant differential cell sensitivity for BN 52205 and BN 52211 for colon and melanoma tumor cells. " 11/01/1991 - "The anti-tumor cytotoxic activity of four newly synthesized aza alkyl lysophospholipids (AALP), namely BN 52205, BN 52207, BN 52208 and BN 52211, was investigated. "
2.	Melanoma (Melanoma, Malignant) 01/01/1994 - "The study of the degree of differential growth inhibition has shown a statistically significant differential cell sensitivity for BN 52205 and BN 52211 for colon and melanoma tumor cells. "
3.	Colonic Neoplasms (Colon Cancer) 01/01/1994 - "We have characterized the cytostatic activity of four ether phospholipids, the methoxy-substituted edelfosine (ET-18-OCH 3), the thio-derivative ilmofosine (BM 41.440), and two new aza-alkylphospholipids, BN 52205 and BN 52211, on a human tumor cell line derived from a colon adenocarcinoma, the HT29. "

Related Drugs and Biologics

1.	BN 52211
2.	Cytostatic Agents
3.	Phospholipid Ethers
4.	Lysophospholipids
5.	BN 52208
6.	BN 52207
7.	ilmofosine
8.	edelfosine