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Kupffer cell receptor

fucose binding; 58 kDa with 550 aa; C-type lectin domain at C-terminus;

Also Known As:

Kupffer cell receptors; receptor, Kupffer cell

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Asialoglycoprotein Receptor: 342
        Kupffer cell receptor: 5
      - Immunologic Receptors: 9
        Kupffer cell receptor: 5
  - Lectins: 6782
    - C-Type Lectins: 976
      - Asialoglycoprotein Receptor: 342
        Kupffer cell receptor: 5

Experts

1.	Bai, Xia: 1 article (11/2021)
2.	Gao, Liang: 1 article (11/2021)
3.	Han, Yue: 1 article (11/2021)
4.	Hoover, Christopher: 1 article (11/2021)
5.	Huang, Dongping: 1 article (11/2021)
6.	Jiang, Miao: 1 article (11/2021)
7.	Jiang, Yizhi: 1 article (11/2021)
8.	Kondo, Yuji: 1 article (11/2021)
9.	Lupu, Florea: 1 article (11/2021)
10.	Marth, Jamey D: 1 article (11/2021)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 10/15/1996 - "We hypothesize that binding of CEA to an 80-kDa Kupffer cell receptor by the peptide sequence Pro-Glu-Leu-Pro-Lys (PELPK) induces cytokine production in the hepatic microenvironment, which then impacts on the formation of hepatic metastasis from colorectal cancer. " 01/01/2017 - "CEA also binds to heterogeneous nuclear RNA binding protein M4 (hnRNP M4), a Kupffer cell receptor protein, and activates Kupffer cells to secrete various cytokines that change the microenvironments for the survival of colorectal cancer cells in the liver. "
2.	Sepsis (Septicemia) 11/01/2021 - "Collectively, these findings identify CLEC4F as a Kupffer cell receptor important for the destruction of desialylated platelets induced by bacteria-derived neuraminidases, which provide new insights into the pathogenesis of thrombocytopenia in disease conditions such as sepsis."
3.	Thrombocytopenia (Thrombopenia) 11/01/2021 - "Collectively, these findings identify CLEC4F as a Kupffer cell receptor important for the destruction of desialylated platelets induced by bacteria-derived neuraminidases, which provide new insights into the pathogenesis of thrombocytopenia in disease conditions such as sepsis."
4.	Neoplasms (Cancer) 09/01/2011 - "In addition, many cell surface lectins: Sialoadhesin-1 (Siglec-1), C-type lectin family 4f (Kupffer cell receptor), and Galactose-binding lectin 9 (Galectin-9) were determined to be up-regulated in the liver of tumor-bearing compared with control mice. "
5.	Neoplasm Metastasis (Metastasis) 10/15/1996 - "We hypothesize that binding of CEA to an 80-kDa Kupffer cell receptor by the peptide sequence Pro-Glu-Leu-Pro-Lys (PELPK) induces cytokine production in the hepatic microenvironment, which then impacts on the formation of hepatic metastasis from colorectal cancer. "

Related Drugs and Biologics

1.	Cytokines
2.	C-Type Lectins (C-Type Lectin)
3.	Galectins (Galectin)
4.	Lectins
5.	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)
6.	Heterogeneous Nuclear RNA
7.	Proteins (Proteins, Gene)
8.	Peptides (Polypeptides)
9.	Carrier Proteins (Binding Protein)
10.	Carbohydrates