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sodium-bile acid cotransporter

amino acid sequence given in first source; GenBank U02028
Also Known As:
ASBT protein; ASBT protein, human; ASBT protein, mouse; IBAT cotransporter; ILBP; NTCP protein, human; Na(+)-taurocholate-cotransporting peptide; Na+-TC cotransport peptide; Na+-bile acid cotransporter; Na+-taurocholate cotransporting polypeptide, human; Ntcp protein, mouse; Ntcp protein, rat; SLC10A1 protein, human; SLC10A2 protein, human; Slc10a1 protein, mouse; Slc10a1 protein, rat; Slc10a2 protein, mouse; Slc10a2 protein, rat; Slc10a4 protein, rat; TC cotransporting polypeptide; apical sodium-dependent bile acid transporter; bile acid cotransporting polypeptide, Ntcp, mouse; bile acid-sodium cotransporter; ileal lipid-binding protein; ileal sodium-dependent bile acid transporter; sodium bile acid cotransporter; sodium taurocholate cotransporting polypeptide; sodium-taurocholate cotransporter; sodium-taurocholate cotransporting polypeptide (Ntcp1); solute carrier family 10 (sodium-bile acid cotransporter family), member 1, human; solute carrier family 10 (sodium-bile acid cotransporter family), member 1, mouse; solute carrier family 10 (sodium-bile acid cotransporter family), member 2, human; solute carrier family 10, member 1, rat; solute carrier family 10, member 2, mouse; solute carrier family 10, member 2, rat
Networked: 186 relevant articles (4 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Watashi, Koichi: 15 articles (11/2021 - 02/2014)
2. Wakita, Takaji: 14 articles (11/2021 - 02/2014)
3. Li, Wenhui: 14 articles (10/2021 - 11/2012)
4. He, Wenhui: 9 articles (01/2018 - 11/2012)
5. Xu, Guangwei: 9 articles (01/2018 - 11/2012)
6. Jing, Zhiyi: 8 articles (01/2018 - 11/2012)
7. Yan, Huan: 8 articles (10/2016 - 11/2012)
8. Tsukuda, Senko: 7 articles (11/2021 - 05/2014)
9. Gao, Zhenchao: 7 articles (01/2018 - 11/2012)
10. Sui, Jianhua: 7 articles (01/2018 - 11/2012)

Related Diseases

1. Liver Diseases (Liver Disease)
10/01/2019 - "Pharmacological inhibition of the ideal apical sodium-dependent bile acid transporter ASBT ameliorates cholestatic liver disease in mice."
01/01/2022 - "The aim of this study was to analyze the relationship between sodium taurocholate cotransporting polypeptide (NTCP) gene varieties and hepatitis B virus (HBV) infection and the progress of HBV-related liver disease. "
01/01/2016 - "This overview focuses on the central roles of farnesoid X receptor, fibroblast growth factor 19, and apical sodium-dependent bile acid transporter for the enterohepatic circulation of bile acids and their potential as new drug targets for the treatment of cholestatic liver disease. "
01/01/2020 - "An increasing focus to target bile acid receptors, responsible for bile acid synthesis and circulation, such as Farnesoid X receptor and apical sodium-dependent bile acid transporter to reduce bile acid synthesis have resulted in clinical trials for treatment of previously untreatable chronic liver diseases such as non-alcoholic steatohepatitis and primary sclerosing cholangitis. "
01/01/2021 - "The hESC-derived HLCs produced by this method express stage-specific markers (including albumin, HNF4α nuclear receptor, and sodium taurocholate cotransporting polypeptide (NTCP)), and show special characteristics related to mature and functional hepatocytes (including indocyanine green staining, glycogen storage, hematoxylin-eosin staining and CYP3 activity), and can provide a platform for the development of HLC-based applications in the study of liver diseases."
2. Infections
3. Liver Cirrhosis (Hepatic Cirrhosis)
4. Fatty Liver
5. Low Back Pain (Lumbago)

Related Drugs and Biologics

1. Bile Acids and Salts (Bile Acids)
2. Messenger RNA (mRNA)
3. Lipids
4. Tacrolimus (Prograf)
5. Coenzyme A (CoA)
6. Cholesterol 7-alpha-Hydroxylase (Cholesterol 7 alpha Hydroxylase)
7. Carrier Proteins (Binding Protein)
8. 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)
9. Proteins (Proteins, Gene)
10. Member 11 Subfamily B ATP Binding Cassette Transporter

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Intra-Articular Injections
4. Aftercare (After-Treatment)