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prepro-factor VII

contains additional 38 amino acids than the active factor

Also Known As:

factor VII precursor; factor VII zymogen

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzyme Precursors: 724
  - Factor VII: 1612
    - prepro-factor VII: 2
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Factor VII: 1612
        prepro-factor VII: 2
  - Protein Precursors: 37
    - Enzyme Precursors: 724
      - Factor VII: 1612
        prepro-factor VII: 2
    - prepro-factor VII: 2
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Factor VII: 1612
    - prepro-factor VII: 2

Related Diseases

1.	Myocardial Ischemia (Ischemic Heart Diseases) 10/01/1989 - "The increased factor VII level in these subjects was caused by elevated factor VII zymogen, not activated factor VII. The results of this study, combined with those of previous studies, suggest that factor VII may be a useful additional marker of the risk for ischemic heart disease and merits further investigation."
2.	Myocardial Infarction 09/01/1991 - "The increased Factor VII level in the patient groups was caused by elevated Factor VII zymogen levels, and not by activated Factor VII. Since FVII:C levels strongly correlated with the titer of thrombin-antithrombin III complexes in all patients, the hypercoagulable state accompanying severe coronary atherosclerosis seems to underlie the increase of FVII and TAT in the stable phase of myocardial infarction."
3.	Coronary Artery Disease (Coronary Atherosclerosis) 09/01/1991 - "The increased Factor VII level in the patient groups was caused by elevated Factor VII zymogen levels, and not by activated Factor VII. Since FVII:C levels strongly correlated with the titer of thrombin-antithrombin III complexes in all patients, the hypercoagulable state accompanying severe coronary atherosclerosis seems to underlie the increase of FVII and TAT in the stable phase of myocardial infarction."

Related Drugs and Biologics

1.	Factor VIIa (Activated Factor VII)
2.	Factor VII (Proconvertin)
3.	Thrombin
4.	Antithrombin III
5.	factor VII clotting antigen