SDZ 215-811

potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors

Also Known As:

(DTPA-Phe(1))-octreotide; (In(III)-DTPA-Phe(1))-octreotide; (In-diethylenetriamine pentaacetic acid-D-Phe)octreotide; (In111-DTPA-Phe(1))-octreotide; 161Tb-(DTPA-Phe(1))-octreotide; In-111 DTPAOC; In-DTPA-D-Phe-octreotide; SDZ-215-811; indium-111-D-Phe(1)-octreotide; octreotide, DTPA-Phe(1)-; terbium-161-(DTPA-Phe(1))-octreotide

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Chun-Hsiung: 1 article (04/2006)
2.	Hen, Shu-Ling: 1 article (04/2006)
3.	Ho, Yung-Jen: 1 article (04/2006)
4.	Hsia, Chien-Chung: 1 article (04/2006)
5.	Hung, Guang-Uei: 1 article (04/2006)
6.	Lin, Wan-Yu: 1 article (04/2006)
7.	Lin, Yung-Chang: 1 article (04/2006)
8.	Luo, Tsai-Yueh: 1 article (04/2006)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1993 - "High uptake of [111In]SDZ 215-811 was observed for the tumor tissue (0.92 +/- 0.07% ID/g; 1 h post injection). " 04/01/2006 - "In this study, we compared the biodistribution and tumor uptake ratio after injection of In-111 DTPAOC and In-111 DOTATOC in rats. " 04/01/2006 - "In addition, 12 rats bearing pancreatic tumors were scanned at 4, 24, and 48 hr after injection of 37 MBq of In-111 DTPAOC or In-111 DOTATOC. " 04/01/2006 - "Twelve rats bearing pancreatic tumors were divided into two groups: six rats were sacrificed at 4 hr after injection of 3.7 MBq of In-111 DTPAOC and another 6 rats were sacrificed at the same time after injection of 3.7 MBq of In-111 DOTATOC. " 01/01/1993 - "As early as 5 min after intravenous injection of [111In]SDZ 215-811 into tumor-bearing rats, the tumors were clearly localized by gamma-camera scintigraphy. "
2.	Islet Cell Adenoma (Islet Cell Tumors) 01/01/1993 - "We report here the in vitro characterization of SDZ 215-811 and the in vivo imaging of an islet cell tumor grown in rats using [111In]SDZ 215-811. "

Related Drugs and Biologics

1.	Edotreotide (SMT 487)
2.	Radiopharmaceuticals

Related Therapies and Procedures

1.	Gamma Cameras (Gamma Camera)
2.	Intravenous Injections