araloside A

structure given in first source; isolated from the root bark of Aralia chinesis L.

Also Known As:

beta-D-Glucopyranosiduronic acid, (3beta)-28-(beta-D-glucopyranosyloxy)-28-oxo-olean-12-en-3-yl 4-O-alpha-L-arabinofuranosyl-

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Oleanolic Acid: 547
        araloside A: 4
      - Sapogenins: 26
        Oleanolic Acid: 547
        araloside A: 4
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - araloside A: 4

Experts

1.	Guo, Dongyan: 2 articles (03/2019 - 10/2018)
2.	Ding, Yanjie: 1 article (06/2019)
3.	Wang, Laifang: 1 article (06/2019)
4.	Zhao, Qing: 1 article (06/2019)
5.	He, Haibo: 1 article (03/2019)
6.	He, Yumin: 1 article (03/2019)
7.	Komatsu, Katsuko: 1 article (03/2019)
8.	Li, Xiaomei: 1 article (03/2019)
9.	Li, Xiaoqin: 1 article (03/2019)
10.	Luo, Huajun: 1 article (03/2019)

Related Diseases

1.	Stomach Ulcer (Gastric Ulcer) 03/01/2019 - "The aim of this study was to elucidate the gastroprotective activity and possible mechanism of involvement of araloside A (ARA) against ethanol- and aspirin-induced gastric ulcer in mice. " 03/01/2019 - "Gastroprotective effect of araloside A on ethanol- and aspirin-induced gastric ulcer in mice: involvement of H+/K+-ATPase and mitochondrial-mediated signaling pathway."
2.	B-Cell Lymphoma (Lymphoma, B Cell) 06/01/2019 - "Meanwhile, araloside A dose-dependently augmented the apoptotic rate and caspase-3/7 activity, increased cytochrome c level and decreased B-cell lymphoma 2 level in MH7A cells. "
3.	Ulcer 03/01/2005 - "Araloside A, a potent inhibitor of gastric lesion and ulcer formation in rats, was isolated from the root bark of Aralia elata through a bioassay-guided separation procedure. "
4.	Breast Neoplasms (Breast Cancer) 10/01/2018 - "The effects of basic parameters, such as compound concentration, time, temperature, paracellular pathway, different intestinal segments were analyzed, and the susceptibility of araloside A absorption process to treatment with various inhibitors, such as the P-gp inhibitor verapamil, the multidrug resistance protein2 inhibitors (MRP2) MK571 and indomethacin, the breast cancer resistance protein (BCRP) inhibitors Ko143 and reserpine, and endocytosis inhibitor chlorpromazine were assessed. "
5.	Rheumatoid Arthritis 06/01/2019 - "Pro-apoptotic and anti-inflammatory effects of araloside A on human rheumatoid arthritis fibroblast-like synoviocytes." 06/01/2019 - "Taken together, araloside A exerted pro-apoptotic and anti-inflammatory effects in rheumatoid arthritis fibroblast-like synoviocytes via inhibition of the nuclear factor kappa B pathway." 06/01/2019 - "However, the effect of araloside A, a triterpenoid saponin extracted from the root bark of Aralia taibaiensis, on rheumatoid arthritis remains unknown. "

Related Drugs and Biologics

1.	Aspirin (Acetylsalicylic Acid)
2.	Ethanol (Ethyl Alcohol)
3.	Caspase 3 (Caspase-3)
4.	Cytochromes c (Cytochrome c)
5.	NF-kappa B (NF-kB)
6.	Verapamil (Calan)
7.	Triterpenes
8.	Saponins
9.	Reserpine (Serpasil)
10.	Proteins (Proteins, Gene)