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streptococcal group B hemolysin

from Steptococcus agalactiae; amino acid sequence given in first source

Also Known As:

GBS beta-hemolysin; Strept B hemolysin; beta-hemolysin, Streptococcal group B

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Hemolysin Proteins: 1059
        streptococcal group B hemolysin: 5
  - Bacterial Proteins: 394
    - streptococcal group B hemolysin: 5

Experts

1.	Nizet, Victor: 3 articles (04/2005 - 06/2002)
2.	Benirschke, Kurt: 1 article (04/2005)
3.	Heldt, Gregory P: 1 article (04/2005)
4.	Hensler, Mary E: 1 article (04/2005)
5.	Liu, George Y: 1 article (04/2005)
6.	Sobczak, Susan: 1 article (04/2005)
7.	Braun, Johann S: 1 article (06/2002)
8.	Pohl, Jürgen: 1 article (06/2002)
9.	Ring, Axel: 1 article (06/2002)
10.	Shenep, Jerry L: 1 article (06/2002)

Related Diseases

1.	Infections 04/15/2005 - "We examined the virulence role of group B Streptococcus (GBS) beta-hemolysin/cytolysin (beta h/c) in a neonatal-rabbit model of GBS pulmonary infection. " 12/01/2002 - "The generation of isogenic GAS and GBS beta-hemolysin-deficient mutants and their analysis using in vitro and in vivo model systems has shown that both toxins function as virulence factors in the pathogenesis of invasive infections."
2.	Lung Injury 01/01/1997 - "There is a direct correlation between the level of GBS beta-hemolysin expression and the ability of GBS to injury lung epithelial cells. "
3.	Sepsis (Septicemia) 06/15/2002 - "This work provides the first evidence that GBS beta-hemolysin plays a crucial role in the pathophysiology of GBS sepsis by inducing liver failure and high mortality."
4.	Liver Failure 06/15/2002 - "This work provides the first evidence that GBS beta-hemolysin plays a crucial role in the pathophysiology of GBS sepsis by inducing liver failure and high mortality."
5.	Pulmonary Edema 05/01/1999 - "We hypothesized that GBS beta-hemolysin contributes to LMvEC injury and exudative pulmonary edema. "

Related Drugs and Biologics

1.	Perforin
2.	Virulence Factors (Pathogenicity Factors)