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BAY u9773

a leukotriene C4 antagonist

Also Known As:

6-(4'-carboxyphenylthio)-5-hydroxy-7,9,11,14-eicosatetraenoic acid; BAY-u9773

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chebolu, Seetha: 1 article (02/2010)
2.	Darmani, Nissar A: 1 article (02/2010)
3.	Ray, Andrew P: 1 article (02/2010)
4.	Wang, Yaozhi: 1 article (02/2010)
5.	Chen, Alex F: 1 article (05/2009)
6.	Ge, Song: 1 article (05/2009)
7.	Liu, Dezhi: 1 article (05/2009)
8.	Liu, Xinfeng: 1 article (05/2009)
9.	Xu, Gelin: 1 article (05/2009)
10.	Yin, Qin: 1 article (05/2009)

Related Diseases

1.	Vomiting 02/25/2010 - "Bay u9773 dose-dependently reduced the percentage of animals vomiting, but did not significantly reduce vomiting frequency. " 02/25/2010 - "The aims of this study were to test the emetic potential of key leukotrienes (LTA(4), LTB(4), LTF(4), and the cysteinyl leukotrienes LTC(4), LTD(4) and LTE(4)), and to investigate whether the leukotriene CysLT(1) receptor antagonist pranlukast or mixed leukotriene CysLT(1/2) receptor antagonist Bay u9773 can prevent the LTC(4)-induced emesis. "
2.	Infarction (Infarctions) 03/01/2008 - "Infarction size in tg mice increased 114% compared with ntg mice 48 hours after I/R; this increase was blocked by the CysLT receptor antagonist BAY-u9773. "
3.	Arteriosclerosis 05/01/2009 - "The observation that progression of cell death aggravated by IL-18 could be attenuated by BAY-u9773 may offer a chance to develop a novel way to treat arteriosclerosis."

Related Drugs and Biologics

1.	Leukotrienes
2.	Emetics
3.	leukotriene D4 receptor (cysteinyl leukotriene receptor)
4.	pranlukast
5.	Interleukin-18 (Interleukin 18)