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SK&F 104976

structure given in first source

Also Known As:

SK&F-104976; SKF 104976

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Fernández, Carlos: 2 articles (05/2005 - 10/2004)
2.	Gómez-Coronado, Diego: 2 articles (05/2005 - 10/2004)
3.	Lasunción, Miguel A: 2 articles (05/2005 - 10/2004)
4.	Ledo, Beatriz: 1 article (05/2005)
5.	Martín, Miguel: 1 article (05/2005)
6.	Suárez, Yajaira: 1 article (05/2005)
7.	Lobo Md, María del Val T: 1 article (10/2004)

Related Diseases

1.

10/15/2004 - "For this, human leukemia cells (HL-60) were incubated in a cholesterol-free medium and treated with SKF 104976, which inhibits cholesterol biosynthesis by blocking sterol 14alpha-demethylase, and the expression of relevant cyclins in the different phases of the cell cycle was analyzed by flow cytometry. "
05/15/2005 - "The human leukemia cells HL-60 and MOLT-4 were cultured in cholesterol-free medium and treated with different sterols in the presence or absence of SKF 104976, a competitive inhibitor of lanosterol 14alpha-demethylase that allows the synthesis of isoprenoid derivatives but not cholesterol. "

Related Drugs and Biologics

1.	Sterols
2.	Cholesterol
3.	Cyclins
4.	Terpenes (Terpenoids)
5.	Lanosterol