vestitone reductase

an isoflavone reductase that catalyzes the oxidation of vestitone to 2'-hydroxyformononetin in the presence of NADP+; also reduces a 2'-hydroxyisoflavone to an isoflavonone; from chick pea & alfalfa; amino acid sequence given in first source

Also Known As:

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Balachandran, Sena Munuswamy: 1 article (07/2021)
2.	Chandra Mohan, Yeshala: 1 article (07/2021)
3.	Durga Rani, Chagamreddy Venkata: 1 article (07/2021)
4.	Mangrauthia, Satendra K: 1 article (07/2021)
5.	Nagalakshmi, Sanivarapu: 1 article (07/2021)
6.	Prakasam, Vellaisamy: 1 article (07/2021)
7.	Prathi, Naresh Babu: 1 article (07/2021)
8.	Srivastava, Sunil K: 1 article (07/2021)
9.	Sundaram, Raman Meenakshi: 1 article (07/2021)
10.	Dos Santos, Lucilene Delazari: 1 article (07/2020)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2009 - "In order to study the medicinal secondary metabolism of Fagopyrum cymosum (Trev.) Meisn, a traditional Chinese medicine with anti-tumor effect, a novel isoflavone reductase-like gene, FcIRL, was cloned using RACE strategy from a cDNA library of high flavonoids-producing callus. "
2.	Dehydration (Water Stress) 11/01/2018 - "A number of transcripts exhibited altered abundance after the acute water stress: reduction of RuBisCO activase and mitochondrial glycine cleavage system H protein, and increase of isoflavone reductase. " 07/01/2020 - "Comparative proteomics allowed to identify four proteins (ATP synthase gamma and alpha, glutamine synthetase and a vacuolar protein) that were more abundant in drought-tolerant species and simultaneously less abundant or unchanged in the drought- sensitive species, an uncharacterized protein found exclusively in plants under drought stress and also 10 proteins (plastid-lipid, ruBisCO activase, ruBisCO, protease ClpA, transketolase, isoflavone reductase, ferredoxin-NADP reductase, malate dehydrogenase, aminobutyrate transaminase and sedoheptulose-1-bisphosphatase) induced exclusively in the drought-tolerant species in response to water stress. "
3.	Leukemia 11/01/1999 - "IgE-binding characteristics and potential allergenicity were investigated by immunoblot, immunoblot inhibition analysis, rat basophil leukemia-cell mediator release assay, and basophil histamine release and compared with those of natural (n) Bet v 5, recombinant (r)Bet v 1, and rBet v 2. Recombinant Bet v 5 has a mass of 33 kd, an isoelectric point of 9.0, and sequence identity of 60% to 80% to isoflavone reductase homologue proteins from various plants. "
4.	Infections 08/01/1995 - "Isoflavonoids and steady-state mRNA levels of phenylalanine ammonia-lyase, chalcone isomerase, and isoflavone reductase were followed during a rapid, nearly synchronous infection of alfalfa (Medicago sativa L.) roots by the vesicular arbuscular fungus Glomus intraradices (Schenck & Smith) to test whether previously indicated suppression of the host defense response is regulated by changes in the steady-state mRNA level. "
5.	Seasonal Allergic Rhinitis (Hay Fever) 07/01/2002 - "The cDNA encodes 306 amino acids with significant sequence similarity to those of plant isoflavone reductase-like proteins, which include a recently identified birch pollen allergen Bet v 5. Western blot analysis demonstrated that recombinant protein was recognized by cedar pollinosis patient IgE. "

Related Drugs and Biologics

1.	Flavonoids
2.	Proteins (Proteins, Gene)
3.	Ribulose-Bisphosphate Carboxylase (Rubisco)
4.	Tissue Plasminogen Activator (Alteplase)
5.	Immunoglobulin E (IgE)
6.	Allergens
7.	Chloroplast Proteins
8.	Profilins (Profilin)
9.	Complementary DNA (cDNA)
10.	Tropomyosin

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)