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PA22-2

a 19-amino acid synthetic peptide; from the laminin A chain sequence

Also Known As:

CSRARKQAASIKVAVSADR-NH2; PA 22-2

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - PA22-2: 5

Experts

1.	Annaert, W: 1 article (04/2009)
2.	Bartic, C: 1 article (04/2009)
3.	Bonroy, K: 1 article (04/2009)
4.	Borghs, G: 1 article (04/2009)
5.	Engelborghs, Y: 1 article (04/2009)
6.	Jans, K: 1 article (04/2009)
7.	Maes, G: 1 article (04/2009)
8.	Reekmans, G: 1 article (04/2009)
9.	Van Meerbergen, B: 1 article (04/2009)

Related Diseases

1.	Neoplasms (Cancer) 11/01/1991 - "As has been reported for many other tumor cells, laminin and the laminin-derived peptide PA22-2, containing the sequence IKVAV, mediate attachment of line 410.4 mammary tumor cells in vitro. " 01/17/1996 - "Neither RC-160 by itself nor a 188Re-labeled peptide, unrelated to somatostatin (PA-22-2, a laminin peptide), demonstrated the reduction in tumor mass observed with 188Re-RC-160. "
2.	Neoplasm Metastasis (Metastasis) 01/01/1992 - "Here we have exposed the clone 10 cells to the synthetic peptide PA22-2, which contains the IKVAV sequence from the A chain of laminin and which, like laminin, induces collagenase IV production and enhances metastasis formation by B16F10 cells. "
3.	Melanoma (Melanoma, Malignant) 06/01/1994 - "However, the IKVAV containing PA22-2 laminin peptide selectively stimulated type IV collagenolytic activity of the A-2058 melanoma cell line, although it did not modulate MMP/TIMP activity. "
4.	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 04/21/2009 - "In this paper we describe the characterization of several self-assembled monolayers (SAMs) for their ability to anchor a laminin-derived synthetic peptide, PA22-2, a peptide known to promote neuronal attachment and stimulate neurite outgrowth. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Laminin (Merosin)
3.	isoleucyl-lysyl-valyl-alanyl-valine
4.	Matrix Metalloproteinases (MMPs)
5.	Collagenases (Collagenase)
6.	Somatostatin (Somatotropin Release-Inhibiting Factor)
7.	vapreotide