HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

sarcalumenin

amino acid sequence has been determined; RN given refers to rabbit clone pGPN1 protein moiety reduced

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - sarcalumenin: 6

Experts

1.	Ohlendieck, Kay: 2 articles (04/2004 - 01/2004)
2.	Carvalho, Leila M: 1 article (03/2021)
3.	Delgado, Josué: 1 article (03/2021)
4.	Estévez, Mario: 1 article (03/2021)
5.	Madruga, Marta S: 1 article (03/2021)
6.	Cheah, Jenice X: 1 article (12/2015)
7.	Gilda, Jennifer E: 1 article (12/2015)
8.	Gomes, Aldrin V: 1 article (12/2015)
9.	Kazmierczak, Katarzyna: 1 article (12/2015)
10.	Szczesna-Cordary, Danuta: 1 article (12/2015)

Related Diseases

1.	Cardiomegaly (Heart Hypertrophy) 10/02/2023 - "These data suggest that CRTC is involved in myocardial cell maintenance and that CaN-CRTC- Sarcalumenin/ tmn signaling represents a novel and conserved pathway underlying cardiac hypertrophy." 10/02/2023 - "The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy." 12/01/2015 - "The physiological model of cardiac hypertrophy (∆43) showed no changes in the levels of Ca(2+)-binding proteins relative to WT, while the pathologic model (A57G) showed the upregulation of three Ca(2+)-binding proteins, including sarcalumenin. "
2.	Muscular Dystrophies (Muscular Dystrophy) 04/15/2004 - "Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy."
3.	Muscular Diseases (Myopathy) 03/15/2021 - "The analysis of sarcoplasmic proteins revealed that muscles severely affected by the myopathy suffered a chronic impairment of physiological (upregulation of sarcoplasmic reticulum Ca2+ ATPase, sarcalumenin and calsequestrin-2) and metabolic processes (downregulation of pyruvate kinase, creatine kinase, and l-lactate dehydrogenase). "
4.	Malignant Hyperthermia 01/01/2004 - "Using immunoblotting, we show here that the ryanodine receptor, calmodulin, junctin, calsequestrin, sarcalumenin, calreticulin, annexin-VI, sarco(endo)plasmic reticulum Ca2+-ATPase, and the dihydropyridine receptor exhibit no major changes in their expression level between normal human skeletal muscle and biopsies from individuals susceptible to malignant hyperthermia. "
5.	Fatigue 09/21/2005 - "Enhanced resistance to fatigue and altered calcium handling properties of sarcalumenin knockout mice."

Related Drugs and Biologics

1.	Calsequestrin
2.	Calcium
3.	Calreticulin
4.	L-Type Calcium Channels (Dihydropyridine Receptor)
5.	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)
6.	Annexin A6
7.	Dystrophin
8.	Pyruvate Kinase
9.	Proteins (Proteins, Gene)
10.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)