griffonin

obtained from the dried powdered roots of Griffonia simplificolia; possible use as an anti-sickling drug for sickle cell disease crisis; RN given refers to (4R-(1Z,4alpha,5beta,6alpha))-isomer, known as lithospermoside

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Wounds and Injuries (Trauma) 07/01/1995 - "In addition, the number of capillaries per unit area of the wound as determined by a stain for Griffonin (Bandeiraea) simplicifolia lectin, and the number of inflammatory cells as identified by an antibody specific for macrophages, were also reduced in the wound area in old rats. "
2.	Sickle Cell Anemia (Hemoglobin S Disease) 04/01/1991 - "It is suggested therefore that griffonin could be a useful anti-sickling drug for sickle cell disease crisis."

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	Griffonia simplicifolia lectins