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3-(2-furylacryloyl)phenylalanylleucine
substrate for carboxypeptidase Y; RN given is for (E)-isomer
Also Known As:
3-(2-furylacryloyl)phenylalanylleucine, (Z)-isomer; FA-Phe-Leu
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Acyclic Acids
Acrylates: 212
3-(2-furylacryloyl)phenylalanylleucine: 1
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Oligopeptides: 519
Dipeptides: 945
3-(2-furylacryloyl)phenylalanylleucine: 1
Related Diseases
1.
Lysosomal Storage Diseases (Lysosomal Storage Disease)
09/20/1995 - "
The three substrates (FA-Phe-Phe, FA-Phe-Leu, and FA-Phe-Ala) which demonstrated the highest specificity (kcat/Km) for the purified enzyme were then used to assay cathepsin A activity in cultured skin fibroblasts from patients affected with galactosialidosis, an inherited lysosomal storage disease caused by the genetic deficiency of cathepsin A.
"
2.
Neuraminidase deficiency with beta-galactosidase deficiency
09/20/1995 - "
The three substrates (FA-Phe-Phe, FA-Phe-Leu, and FA-Phe-Ala) which demonstrated the highest specificity (kcat/Km) for the purified enzyme were then used to assay cathepsin A activity in cultured skin fibroblasts from patients affected with galactosialidosis, an inherited lysosomal storage disease caused by the genetic deficiency of cathepsin A.
"
Related Drugs and Biologics
1.
Cathepsin A
2.
Enzymes
3.
N-(3-(2-furyl)acryloyl)phenylalanine