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3'-deoxyinosine
structure given in first source
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Inosine: 893
3'-deoxyinosine: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Inosine: 893
3'-deoxyinosine: 1
Ribonucleosides: 49
Inosine: 893
3'-deoxyinosine: 1
Related Diseases
1.
Neoplasms (Cancer)
01/01/1988 - "
3'-dANO and 2'-dCF increased the survival time of tumor-bearing mice by a factor of 2. In vitro studies showed that the 3'-dANO resistant Ehrlich cells initiate the metabolism of 3'-dANO by a reduction to 3'-deoxyadenosine, which is converted primarily to 3'-deoxyinosine by adenosine deaminase and, to a small extent, phosphorylated to the cell toxic agent 3'-dATP.
"
Related Drugs and Biologics
1.
Adenosine Deaminase
2.
cordycepin
3.
A-factor (Streptomyces)