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2,2,3,3,5,5- hexamethyl- 1- pyrrolidinyloxyl

Also Known As:

HMPO

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Heterocyclic Oxides
  - Cyclic N-Oxides: 3
    - 2,2,3,3,5,5-hexamethyl-1-pyrrolidinyloxyl: 6

Experts

1.	Abbate, Mauro: 1 article (01/2021)
2.	Benigni, Ariela: 1 article (01/2021)
3.	Cerullo, Domenico: 1 article (01/2021)
4.	Corna, Daniela: 1 article (01/2021)
5.	Macconi, Daniela: 1 article (01/2021)
6.	Remuzzi, Giuseppe: 1 article (01/2021)
7.	Rizzo, Paola: 1 article (01/2021)
8.	Rottoli, Daniela: 1 article (01/2021)
9.	Zoja, Carlamaria: 1 article (01/2021)
10.	Holzer, Michael: 1 article (01/2019)

Related Diseases

1.	Tuberculosis (Tuberculoses) 11/24/2014 - "In the search for new therapeutic tools against tuberculosis and to further address the therapeutic potential of pyridine-2-thiol 1-oxide (Hmpo) metal complexes, two new octahedral [M(III)(mpo)3] complexes, with M = Ga or Bi, were synthesized and characterized in the solid state and in solution. "
2.	Proteinuria 01/01/2021 - "Challenging hMPO-immunized rats with the anti-GBM serum led to more glomerular neutrophil infiltration and MPO release, and severe haematuria, heavy proteinuria, and higher blood urea nitrogen than hMPO alone. "
3.	Parkinson Disease (Parkinson's Disease) 01/01/2019 - "Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment."
4.	Paralysis (Palsy) 01/01/2019 - "Further, hMPO expression in the A53T model resulted in earlier onset of end stage paralysis. "
5.	Inflammation (Inflammations) 01/01/2015 - "As an early visitor to the injured loci, neutrophil-derived human Myeloperoxidase (hMPO) offers an attractive protein target to modulate the inflammation of the host tissue through suitable inhibitors. "

Related Drugs and Biologics

1.	Peroxidase (Myeloperoxidase)
2.	Proteins (Proteins, Gene)
3.	Coordination Complexes
4.	Synucleins
5.	Biomarkers (Surrogate Marker)
6.	Urea (Carbamide)
7.	Solutions
8.	Peptides (Polypeptides)
9.	Nitrogen
10.	Autoantibodies