PC6 extract (PC6)

04/01/2013 - "EA on PC6 is effective in the prevention of PONV, and pre-operative acupuncture is more effective than post-operative acupuncture."
04/01/2014 - "Our findings favor a combination of PC6 and LI4 stimulation for the treatment of postoperative nausea and vomiting."
01/01/2013 - "Besides PC6, PC6 combined with other acupoint(s) and other alternative acupoint(s) might be beneficial in prevention and treatment of PONV, the evidence justifies future high-quality studies."
01/01/2014 - "The primary aim of the proposed research is to test the efficacy of PC6 acupoint stimulation versus placebo for reducing PONV in cardiac surgery patients. "
01/01/2015 - "Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting."

02/01/2005 - "EA (10 Hz) at PC6 significantly reduced the number of episodes of retching and vomiting. "
07/01/1997 - "The efficacy of intra-operative acupuncture at the PC6 point in the prevention of postoperative nausea or vomiting was studied. "
01/01/2013 - "Meta-analysis showed that PC6 acupuncture significantly reduced the number of cases of early vomiting (postoperative 0-6h) (RR=0.36, 95%CI 0.19,0.71; P=0.003) and nausea (postoperative 0-24h) (RR=0.25, 95%CI 0.10,0.61; P=0.002), but not early nausea (postoperative 0-6h) (RR=0.64, 95%CI 0.34,1.19; P=0.150) and vomiting (postoperative 0-24h) (RR=0.82, 95%CI 0.48,1.38; P=0.450). "
10/01/2000 - "Acupuncture on the point PC6 above the wrist on the palmar side has been found to prevent some types of nausea and vomiting. "
10/01/2006 - "This preliminary study seems to suggest that a bioenergetic approach by acupressure on PC6 point may be effective in the treatment of chemotherapy-induced vomiting resistant to the conventional pharmacological strategies, as previously demonstrated for vomiting occurring during pregnancy."

03/01/2008 - "Good clinical evidence has been reported for the effect of PC6 acupuncture in preventing or attenuating postoperative and pregnancy related nausea. "
12/01/2014 - "Our results indicate that acupoint PC6 was effective for controlling nausea during the maxillary impression-taking procedure. "
12/01/2014 - "The objective of this study was to evaluate the effectiveness of acupuncture point PC6 (Neiguan) in controlling nausea during intraoral impression taking. "
12/01/2014 - "Nausea control by needling at acupuncture point Neiguan (PC6) during an intraoral impression-taking procedure."
01/01/2013 - "Meta-analysis showed that PC6 acupuncture significantly reduced the number of cases of early vomiting (postoperative 0-6h) (RR=0.36, 95%CI 0.19,0.71; P=0.003) and nausea (postoperative 0-24h) (RR=0.25, 95%CI 0.10,0.61; P=0.002), but not early nausea (postoperative 0-6h) (RR=0.64, 95%CI 0.34,1.19; P=0.150) and vomiting (postoperative 0-24h) (RR=0.82, 95%CI 0.48,1.38; P=0.450). "

08/01/1992 - "In vitro cytotoxicity and in vivo antitumor studies were carried out using the ADJ/PC6 plasmacytoma. "
01/01/1985 - "Activity has been shown in preclinical studies in mice bearing intraperitoneal P388 and L1210 leukaemias, ADJ-Pc6 plasmacytoma and a variety of solid tumours. "
01/01/1998 - "However, initial in vivo testing against a solid mouse plasmacytoma (PC6) and P388 leukaemia has not revealed significant activity."
07/01/1996 - "to ADJ/PC6 plasmacytoma bearing mice (ED90 of 1.0 and 0.4 versus 5.7 and 4.2 mg/kg, TI (therapeutic index) of 14 and 37 versus 5.3 and 4.2). "
01/01/1996 - "Antitumour activity was assessed in the bifunctional alkylating-agent-sensitive murine plasmacytoma ADJ/PC6 using a variety of administration protocols. "

05/01/2012 - "Actually there are no studies in medical literature as to the efficacy of treating PC6 acupoint for gastrointestinal symptoms in migraine attacks. "
05/01/2012 - "The patients were treated randomly for a total of six migraine attacks: three with the application of a device, the Sea-Band(®) wristband, which applies continual pressure to the PC6 acupoint (phase SB), and three without it (phase C). "
05/01/2012 - "Our study aimed at verifying if pressure applied to the acupoint PC6 was effective on nausea during migraine. "
05/01/2012 - "Also the number of patients who reported at least a 50 % reduction in the nausea score was significantly higher in phase SB than in phase C at 30, 60 and 120 min. Moreover, the consistency of the treatment (response in at least two out of three treated attacks) was reached in 28 % patients at 60 min; in 40 % at 120 min and 59 % at 240 min. Our results encourage the application of PC6 acupressure for the treatment of migraine-associated nausea."