SA 3443
a cyclic disulfide compound with hepatoprotective effects; posssible protective agent in treatment of liver diseases; RN given refers to (R)-isomer; RN for cpd without isomeric designation not available 8/91
Also Known As:
SA-3443; SA3443; hexahydro-7,7-dimethyl-6-oxo-1,2,5-dithiazocine-4-carboxylic acid
Networked: 7
relevant articles (2 outcomes,
1 trials/studies)
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Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Wounds and Injuries (Trauma)
09/01/1991
- " These findings indicate that SA3443 protects the liver against chronic liver injuries induced by CCl4 and heterogeneous serum." 01/01/1991
- " These results suggest that SA3443 provides considerable protection against immunological liver injuries, and that the efficacy of SA3443 might be partially related to an inhibition of the increase in lymphocyte-activating factor activity." 09/01/1991
- " The protective effects of SA3443, a novel cyclic disulfide, on chronic liver injuries in rats." 01/01/1991
- " Protective effect of (4R)-hexahydro-7,7-dimethyl-6-oxo-1,2,5-dithiazocine-4-carboxylic acid (SA3443), a novel cyclic disulfide, on immunologically induced liver injuries in mice." 02/01/1991
- " The effects of SA3443, a novel cyclic disulfide compound, on acute liver injuries induced by carbon tetrachloride (CCl4), D-galactosamine and DL-ethionine were studied in rats or mice. "
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2. | Necrosis
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3. | Fibrosis (Cirrhosis)
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4. | Choroidal Neovascularization
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5. | Acute Liver Failure (Fulminant Hepatic Failure)
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Related Drugs and Biologics
Related Therapies and Procedures