phosphoenolpyruvate carboxylase kinase

from Bryophyllum fedtschenkoi plant & maize; phosphorylates phosphoenolpyruvate carboxylase on serine near the N-terminus; activity controlled by circadian rhythms, do not confuse with Phosphoenolpyruvate Carboxylase

Also Known As:

PEP carboxylase kinase; PEPC kinase

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        phosphoenolpyruvate carboxylase kinase: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - phosphoenolpyruvate carboxylase kinase: 1

Experts

1.	Bhanot, Sanjay: 1 article (07/2009)
2.	Erion, Derek M: 1 article (07/2009)
3.	Gao, Qian: 1 article (07/2009)
4.	Gillum, Matthew P: 1 article (07/2009)
5.	Horvath, Tamas L: 1 article (07/2009)
6.	Hsiao, Jennifer J: 1 article (07/2009)
7.	Iwasaki, Takanori: 1 article (07/2009)
8.	Monia, Brett P: 1 article (07/2009)
9.	Murray, Susan F: 1 article (07/2009)
10.	Nagai, Yoshio: 1 article (07/2009)

Related Diseases

Hyperglycemia

07/07/2009 - "Because Sirtuin 1 (SirT1) induces hepatic gluconeogenesis during fasting through the induction of phosphoenolpyruvate carboxylase kinase (PEPCK), fructose-1,6-bisphosphatase (FBPase), and glucose-6-phosphatase (G6Pase) gene transcription, we hypothesized that reducing SirT1, by using an antisense oligonucleotide (ASO), would decrease fasting hyperglycemia in a rat model of T2DM. "

Related Drugs and Biologics

1.	Sirtuin 1
2.	Antisense Oligonucleotides
3.	Fructose-Bisphosphatase
4.	Glucose-6-Phosphatase (Glucose 6 Phosphatase)