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trans-sialidase

transfers alpha(2-3)-linked sialic acid from extrinsic host-derived macromolecules to parasite surfaced molecules leading to the assembly of SSp-3, a trypomastigote-specific epitope; amino acid sequence of SAPA antigen given in second source
Also Known As:
PDNF protein, Trypanosoma cruzi; SAPA antigen, Trypanosoma cruzi; SAPA protein, Trypanosoma cruzi; T cruzi trans-sialidase; Trypanosoma cruzi, trans-sialidase; alpha2,3-trans-sialidase; gp38 trans-sialidase; parasite-derived neurotrophic factor, Trypanosoma cruzi; shed acute-phase antigen, Trypanosoma; trans-sialidase, Trypanosoma cruzi
Networked: 124 relevant articles (6 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Campetella, Oscar: 9 articles (07/2021 - 03/2002)
2. Tarleton, Rick L: 8 articles (01/2016 - 06/2003)
3. Todeschini, Adriane R: 7 articles (01/2014 - 05/2002)
4. Mucci, Juan: 6 articles (01/2020 - 03/2002)
5. Freire-de-Lima, Leonardo: 5 articles (01/2021 - 01/2008)
6. Roitberg, Adrian E: 5 articles (10/2013 - 04/2009)
7. Rodrigues, Mauricio M: 5 articles (09/2009 - 09/2003)
8. Mendonça-Previato, Lucia: 4 articles (01/2021 - 01/2008)
9. Alzari, Pedro M: 4 articles (10/2018 - 01/2005)
10. Cabrera, Gabriel: 4 articles (01/2018 - 03/2015)

Related Diseases

1. Chagas Disease (American Trypanosomiasis)
2. Atherosclerosis
3. Infections
4. Anemia
5. Neglected Diseases

Related Drugs and Biologics

1. Cholesterol
2. gamma-sitosterol (beta-sitosterol)
3. N-Acetylneuraminic Acid (Sialic Acid)
4. Virulence Factors (Pathogenicity Factors)
5. Antigens
6. Subunit Vaccines
7. ISCOMATRIX
8. Membrane Proteins (Integral Membrane Proteins)
9. cruzipain
10. Neuraminidase (Sialidase)

Related Therapies and Procedures

1. Aftercare (After-Treatment)
2. Drug Therapy (Chemotherapy)
3. Therapeutics