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YM 13650

structure given in first source; RN from Toxlit

Also Known As:

2-(3-carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole; YM-13650

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Benzothiazoles: 40
        YM 13650: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzothiazoles: 40
      - YM 13650: 2

Related Diseases

1.	Shock 02/01/1991 - "On the other hand, YM-13650 did not show any inhibitory effect on passive cutaneous anaphylaxis in rats (type I), Forssman shock in guinea pigs (type II) and carrageenin-induced paw edema in rats. "
2.	Proteinuria 04/01/1991 - "In preventative experiments in lupus mice treated from 8 weeks of age, YM-13650 in comparison with the control group showed a lesser degree of proteinuria throughout the experimental period. "
3.	Nephritis 04/01/1991 - "[Effects of YM-13650 on experimental nephritis in rats and mice]." 04/01/1991 - "These results show that YM-13650 has preventative and therapeutic effects on experimental nephritis in rats and mice, and it may prove valuable as an anti-nephritic drug." 04/01/1991 - "We investigated the effects of YM-13650, 2-(m-carboxyacetoxyphenyl) imidazo [2, 1-b] benzothiazole, on BSA-immune complex nephritis in rats and lupus nephritis in NZB/W F1 mice. " 04/01/1991 - "In preventative experiments on immune complex nephritis in rats, YM-13650 (10 approximately 100 mg/kg, p.o.) dose-dependently inhibited the increase in urinary protein, serum cholesterol, and urea nitrogen. "
4.	Lupus Nephritis 04/01/1991 - "We investigated the effects of YM-13650, 2-(m-carboxyacetoxyphenyl) imidazo [2, 1-b] benzothiazole, on BSA-immune complex nephritis in rats and lupus nephritis in NZB/W F1 mice. "
5.	Hypersensitivity (Allergy) 02/01/1991 - "These results indicate that YM-13650 suppresses not only cell-mediated immune responses but also type III allergic reactions without any influence on type I and type II allergic reactions as well as an acute inflammatory reaction." 02/01/1991 - "YM-13650 in the dose range of 6.3 to 100 mg/kg, p.o., inhibited the picrylchloride-induced delayed type hypersensitivity (Pc-DTH) in mice when administered during the induction and the effector phases. " 02/01/1991 - "The effects of YM-13650 on experimental animal models of cell-mediated immune responses (type IV), antibody formation and type I to type III allergic reactions were investigated. " 02/01/1991 - "[Effects of YM-13650 on type I to type IV allergic reactions and immune responses in animals]."

Related Drugs and Biologics

1.	Therapeutic Uses
2.	Urea (Carbamide)
3.	Nitrogen
4.	Cholesterol
5.	Carrageenan
6.	Blood Proteins (Serum Proteins)
7.	Antigen-Antibody Complex (Immune Complex)
8.	benzothiazole