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HLA-DQB1 antigen (HLA DQB1)

Subscribe to New Research on HLA-DQB1 antigen

associated with genetic susceptibility to insulin-dependent diabetes in a black population

Also Known As:

HLA DQB1; HLA DQB1 *0603; HLA DQB1 0603 antigen; HLA DQB1*0502; HLA DQB1*0502 antigen; HLA DQB1*0603 antigen; HLA-DQB1; HLA-DQB1*0502; HLA-DQB1*0601; HLA-DQB1*0601 antigen; HLA-DQB1*0603; HLA-DQbeta1

Networked: 417 relevant articles (10 outcomes, 58 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Mignot, Emmanuel: 6 articles (10/2015 - 01/2013)
2.	Lincoln, Matthew R: 5 articles (05/2009 - 10/2005)
3.	Ebers, George C: 5 articles (05/2009 - 10/2005)
4.	Dyment, David A: 5 articles (05/2009 - 10/2005)
5.	Ilonen, J: 5 articles (06/2006 - 01/2000)
6.	Lin, Ling: 4 articles (10/2015 - 01/2013)
7.	Plazzi, Giuseppe: 4 articles (10/2014 - 07/2013)
8.	Granados, Julio: 4 articles (01/2013 - 05/2004)
9.	Vierkant, Robert A: 4 articles (10/2011 - 05/2008)
10.	Poland, Gregory A: 4 articles (10/2011 - 05/2008)

Related Diseases

1.	Infection 01/01/2011 - "In addition to IL28B CC-genotype, HLA DQB10301 helps in predicting natural clearance of HCV after acute infection." 06/01/2000 - "Recent evidence suggests that spontaneous clearance of hepatitis C virus (HCV) may be associated with the HLA DQB10301 allele but there is still some debate over the role of other alleles and HLA haplotypes in HCV infection. " 08/01/2006 - "The study aimed to explore whether the HLA-DQB1 allele polymorphisms are associated with the outcomes of HBV infection in the Chinese Han population. " 01/01/2015 - "Correlation of HLA-DQB1 gene polymorphism of Xinjiang Uygur with outcome of HBV infection." 10/01/2013 - "The results suggest that HLA-DQB1 alleles and critical amino acid differences in the peptide-binding pockets of HLA-DQB1 alleles might have role in influencing infection and pathogenesis of CHIKV. "
2.	Asthma (Bronchial Asthma) 01/01/2010 - "In evaluating the HLA association, there was a decreased frequency of HLA-DQB103 in Alternaria-sensitive moderate severe asthmatic children consistent with previous studies suggest that HLA-DQB103 may be protective against the development of mold-sensitive severe asthma." 10/01/2015 - "Our study illustrates cell-type-specific regulation of the expression of asthma-related genes documenting SNPs in TSLP, GSDMB, IL33, HLA-DQB1, C11orf30, DEXI, CDHR3, and ZBTB10 affect asthma risk through cis-regulation of its gene expression. " 01/01/2011 - "Among the asthma genes identified in genome wide association studies, ROBO1, RORA, HLA-DQB1, IL2RB and PDE10A were differentially expressed during human lung development. " 11/01/2010 - "There was decreased frequency of HLA-DQB103 in Alternaria-sensitive moderate-severe asthma, suggesting HLA-DQB103 may be protective of the development of Alternaria-sensitive severe asthma." 11/01/2010 - "The frequency of HLA-DQB1*03 alleles was significantly decreased in mold and Alternaria-sensitive moderate-severe asthma. "
3.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/01/2004 - "In this study, we have investigated the frequencies of TAP1 and TAP2 alleles in a group of 226 persons, living in La Reunion Island, consisting of 70 patients with insulin-dependent diabetes mellitus (IDDM) and most of their first degree relatives (i.e., 156 parents and full sibling subjects) and previously HLA DQB1, DQA1, and DRB1 genotyped. " 10/01/1997 - "Both studies rely on screening of newborn infants for IDDM susceptibility alleles at the HLA-DQB1 locus. " 01/01/2005 - "[HLA DQB1 genotyping in latent autoimmune diabetes of adults (LADA)]." 03/01/2004 - "HLA-DQB1 alleles may influence the surface expression of DQ molecules in lymphomononuclear cells of type 1 diabetes mellitus patients." 02/01/2003 - "The prevalence of HLA-DQB10302, -DR4, -DR3, and -DR3/DR4 risk alleles and the DR4-DQB10302 high-risk haplotype did not differ in the two forms of autoimmune diabetes."
4.	Melanoma (Melanoma, Malignant) 07/01/1998 - "HLA-DQB10303 and 0301 alleles influence susceptibility to and prognosis in cutaneous malignant melanoma in the British Caucasian population." 05/01/1997 - "The frequency of HLA-DQB10302 was increased, while those of DQA10101(04), -DQA10401 and DRB10802 were decreased in melanoma patients compared with controls. " 11/29/1996 - "These advantages make it the procedure of choice for screening melanoma patients and others for the presence of the HLA-DQB1 * 0301 allele." 11/29/1996 - "Comparison of the single-step PCR method with standard PCR-SSO oligotyping on 63 blinded samples from Caucasian melanoma patients demonstrated complete agreement between the two methods in the detection of HLA-DQB1 * 0301. " 11/29/1996 - "A rapid screening test for HLA-DQB1 * 0301 may be useful in clinical research involving melanoma patients. "
5.	Cervical Intraepithelial Neoplasia 07/04/1992 - "HLA-DQB1*03 and cervical intraepithelial neoplasia type III." 07/01/2015 - "The distribution of HLA-DQB1 G > A and IL-1β -511 C/T polymorphisms was determined in HPV-negative cervical swabs from normal women (N = 111) and compared with cervical swabs of HPV-cleared normal women (once HPV infected followed by natural clearance of the infection, N = 86), HPV16/18-positive cervical intraepithelial neoplasia (CIN, N = 41) and CaCx biopsies (N = 107). " 06/01/2007 - "In this study, the HLA DQB1 alleles among 221 southern Chinese women with cervical intraepithelial neoplasia grade III (CIN III)/invasive cervical carcinoma (ICC) were compared to 191 controls. "

Related Drugs and Biologics

1.	HLA-DRB1 antigen (HLA DRB1)
2.	HLA-B Antigens (HLA-B)
3.	HLA-A Antigens (HLA-A)
4.	HLA-DQA1 (HLA DQA1)
5.	Antigens
6.	HLA-C Antigens (HLA-C)
7.	Aspartic Acid (Aspartate)
8.	Antibodies
9.	DNA (Deoxyribonucleic Acid)
10.	Autoantibodies

Related Therapies and Procedures

1.	Transplantation (Transplant Recipients)
2.	Stem Cell Transplantation
3.	Transplants (Transplant)
4.	Breast Implants (Breast Implant)