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1- acyl- 2- acetyl- sn- glycero- 3- phosphocholine

structural analog of PAF containing a fatty acyl group in the sn-1 position

Also Known As:

1-acyl-2-acetyl-GPC

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Glycerophospholipids: 689
        Phospholipid Ethers: 36
        Platelet Activating Factor: 2984
        1-acyl-2-acetyl-sn-glycero-3-phosphocholine: 2
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Platelet Activating Factor: 2984
    - 1-acyl-2-acetyl-sn-glycero-3-phosphocholine: 2
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Platelet Activating Factor: 2984
      - 1-acyl-2-acetyl-sn-glycero-3-phosphocholine: 2

Experts

1.	Kulikov, V I: 1 article (06/2002)
2.	Muzya, G I: 1 article (06/2002)

Related Diseases

1.	Thrombosis (Thrombus) 05/15/1991 - "In light of the integral role which the vascular endothelial cell plays in the regulation of thrombosis, these findings also suggest that the production of 1-acyl-2-acetyl-GPC may be biologically important."
2.	Hypercholesterolemia 06/01/2002 - "The compounds 1-acyl-2-acetyl-sn-glycero-3-phosphocholine (1-acyl-PAF) and 1-alk-1;-enyl-2-acetyl-sn-glycero-3-phosphocholine (1-alkenyl-PAF) only slightly inhibited the endogenous superoxide production in the leukocytes of hypercholesterolemia individuals. "

Related Drugs and Biologics

1.	Superoxides (Superoxide)
2.	Phosphorylcholine (Phosphocholine)