D 17872

benzylethylenediamine derivative of cisplatin; no other info avail; did not substantially activate HIV long terminal repeat; less toxic than cisplatin

Also Known As:

D-17872; D17872; Platinum, dichloro(3-(4-chlorophenyl)-1,2-propanediamine-N,N')-, (SP-4-3)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Neoplasms (Cancer) 01/01/1993 - "The antitumor activity of the platinum complex D-17872 is associated with tumor cell differentiation." 01/01/1993 - "Moreover, the M5076 reticulum cell sarcoma implanted into the subrenal capsule and the DMBA-induced mammary tumor of the rat were inhibited by D-17872 to a greater extent than by cisplatin (min. T/C: D-17872 -3%, cisplatin 11%). "
2.	Experimental Melanoma 01/01/1993 - "ILS: D-17872 163%, cisplatin 163%) and murine B16 melanoma. "
3.	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/01/1993 - "Moreover, the M5076 reticulum cell sarcoma implanted into the subrenal capsule and the DMBA-induced mammary tumor of the rat were inhibited by D-17872 to a greater extent than by cisplatin (min. T/C: D-17872 -3%, cisplatin 11%). "
4.	Leukemia L1210 01/01/1993 - "ILS: D-17872 132%, cisplatin 55%) and L1210 leukemia (max. "
5.	Leukemia 01/01/1993 - "ILS: D-17872 43%, cisplatin 38%), L5222 leukemia of the rat (max. "

Related Drugs and Biologics

1.	D 17872
2.	Platinum
3.	Cisplatin (Platino)
4.	Capsules (Microcapsules)