carnosol

01/01/2023 - "The objective of this study is to observe the effect of carnosol on the tumor phenotype and signaling pathway of HCC cells. "
01/01/2018 - "This study was designed to gather the recent literature findings from 2010 to 2016 on the cancer anti-tumor activities of carnosol and probably involved mechanisms. "
10/08/2020 - "In cancer cells, carnosol has been demonstrated to inhibit cell proliferation and survival, reduce migration and invasion, and significantly enhance apoptosis. "
08/01/2020 - "We conclude that TDP1 and TDP2 play important roles in the anti-cancer effect of carnosol."
08/01/2020 - "Carnosol is a natural compound with pharmacological action due to its anti-cancer properties. "

11/15/2023 - "Carnosol (CS) was found in our previous study to exhibit ameliorating effects on cancer cachexia. "
11/15/2023 - "Carnosol analogue WK-63 alleviated cancer cachexia by inhibiting NF-κB and activating AKT pathways in muscle while inhibiting NF-κB and AMPK pathways in adipocyte."
12/01/2022 - "The protective effects of carnosol on myotubes against atrophy of C2C12 myotubes induced by miR-183-5p, based on both its inhibiting effects on MuRF-1 and Atrogin-1-mediated protein degradation and its ability of keeping the mitochondrial respiration, might contribute to its ameliorating effects on cancer cachexia."
12/01/2022 - "Carnosol, which exhibited ameliorating effects on cancer cachexia of C26 tumour-bearing mice in our previous study, alleviated atrophy of C2C12 myotubes induced by exosomes of C26 tumour cells in the present study. "
01/01/2021 - "Carnosol and its analogues attenuate muscle atrophy and fat lipolysis induced by cancer cachexia."

04/01/2014 - "In the present study, we found that carnosol significantly reduced the viability of human colon cancer (HCT116) cells in a concentration- and time-dependent manner. "
04/01/2014 - "Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells."
01/01/2017 - "Nano-liquid Chromatography-orbitrap MS-based Quantitative Proteomics Reveals Differences Between the Mechanisms of Action of Carnosic Acid and Carnosol in Colon Cancer Cells."
12/07/2016 - "Comparative Study of Green Sub- and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on Colon Cancer Cells."
10/07/2014 - "In this work, the contribution of carnosic acid (CA) and carnosol (CS), two major compounds present in rosemary, against colon cancer HT-29 cells proliferation is investigated using a comprehensive Foodomics approach. "

07/14/2009 - "To investigate the possible protective effects of carnosol on liver injury induced by intestinal ischemia reperfusion (I/R). "
07/14/2009 - "Prophylaxis with carnosol attenuates liver injury induced by intestinal ischemia/reperfusion."
09/01/2010 - "The purpose of this study was to investigate the preconditioning effects of carnosol on lung injury induced by intestinal ischemia/reperfusion (II/R). "
09/01/2010 - "Protective effect of carnosol on lung injury induced by intestinal ischemia/reperfusion."
12/01/2018 - "Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide."

01/01/2009 - "In the present study, carnosol was tested for its ability to sensitize leukemia cells to chemotherapeutic agents. "
09/10/2001 - "Carnosol-induced apoptosis and downregulation of Bcl-2 in B-lineage leukemia cells."
01/01/2009 - "These data show that carnosol blocks the terminal apoptotic events induced by chemotherapeutic drugs and suggest that increased dietary intake of carnosol may potentially decrease the effectiveness of some standard chemotherapy treatments used for leukemia."
06/01/2011 - "One agent in particular, carnosol, has been evaluated for anti-cancer property in prostate, breast, skin, leukemia, and colon cancer with promising results. "
09/10/2001 - "These results suggest that carnosol may be useful as a novel chemotherapeutic agent against B-lineage leukemias, and possibly other types of cancers that express high levels of the protective protein, Bcl-2."