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gastrofenzin (AN(5))

structure given in first source

Also Known As:

AN(5); AN5; 2-methyl-4-(4-chlorophenyl)-8-((ethoxycarbonyl)amino)-1,2,3,4-tetrahydroisoquinoline; gastrofensin

Networked: 20 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - Tetrahydroisoquinolines: 44
        gastrofenzin: 20

Experts

1.	Chen, Zhe: 1 article (10/2019)
2.	Du, Hongxia: 1 article (10/2019)
3.	Li, Hongfei: 1 article (10/2019)
4.	Liu, Ronghan: 1 article (10/2019)
5.	Ning, Bin: 1 article (10/2019)
6.	Su, Yanlin: 1 article (10/2019)
7.	Wang, Wenzhao: 1 article (10/2019)
8.	Gulati, Ashu: 1 article (06/2017)
9.	Joshi, Robin: 1 article (06/2017)
10.	Kumar, Dharmesh: 1 article (06/2017)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 01/01/2023 - "This study aimed to evaluate and compare the cytotoxic effect of CAP and its analogs N-benzylbutanamide (AN1), N-(3-methoxybenzyl) butanamide (AN2), N-(4-hydroxy-3-methoxybenzyl) butanamide (AN3), N-(4-hydroxy-3-methoxybenzyl) hexanamide (AN4) and N-(4-hydroxy-3-methoxybenzyl) tetradecanamide (AN5) on the hepatoma cells of Rattus norvegicus using the MTT test. "
2.	Tuberculosis (Tuberculoses) 12/01/2011 - "tuberculosis H37Rv (ATCC 27294) and Mycobacterium bovis AN5. " 05/01/2011 - "tuberculosis H37Rv ATCC 27294 and Mycobacterium bovis AN5 were tested. " 11/01/1971 - "1. The antibacterial activity in vitro of dihydro-1,3-oxazine derivatives with aromatic rings condensed in positions 5, 6 was examined.2. Of more than thirty compounds examined, two (T 615 and T 638) showed marked activity against various strains of Mycobacterium tuberculosis at concentrations below 2 mug/ml.3. These two compounds also showed marked activity against Escherichia coli, Clostridium pneumoniae and Salmonella typhi.4. Both showed marked activity in vivo against tuberculosis produced in mice and guinea-pigs by various strains of Mycobacterium such as human strain ;Sz', bovine ;An 5' and H37Rv non-resistant and resistant to isonicotinic acid hydrazide (INH), streptomycin (SM) and p-aminosalicylic acid (PAS)." 06/01/2004 - "tuberculosis) and AN5 (Mycobacterium bovis)--to 4 medications--isoniazid, rifampin, streptomycin and ethambutol. "
3.	Neoplasms (Cancer) 01/01/2023 - "Transduction did not alter GEM phenotype as evaluated by flow cytometry, but αIL-10 GEMs produced measurable quantities of BT-063 in the TME that was associated with an ~5-fold higher rate of tumor cell apoptosis than control." 06/01/2017 - "Anthocyanins AN1-4 and crude extract AN5 showed cytotoxicity on C-6 cancer cells and high relative fluorescence units (RFU) at 200 μg/mL suggesting promising apoptosis induction activity as well as influential immunostimulatory potential. "
4.	Infections 01/01/2017 - "Pseudomonas syringae infection experiments with AN4 and AN5 overexpression lines demonstrated a significantly higher tolerance of several transgenic lines to P. " 08/01/2003 - "bovis AN5 is suitable to detect infection with presently prevalent M. "
5.	Wounds and Injuries (Trauma) 10/01/2019 - "We used an oxygen glucose deprivation method to model astrocytes ischemia in vitro and tested proliferation, migration, and excitability of A2s using an 5-ethynyl -2'-deoxyuridine kit, wound scratch assay, and calcium-ion probe. "

Related Drugs and Biologics

1.	caproamide
2.	Tuberculin (PPD)
3.	Streptomycin (Streptomycin Sulfate)
4.	Isoniazid (Ftivazide)
5.	Complex Mixtures
6.	Rifampin (Rifampicin)
7.	Reserpine (Serpasil)
8.	Ranitidine (Zantac)
9.	Proteins (Proteins, Gene)
10.	Aminosalicylic Acid (Rezipas)

Related Therapies and Procedures

1.	Punctures
2.	Ligation