gibbon ape leukemia virus receptor

a high-affinity sodium-dependent phosphate transporter; amino acid sequence in second source; GenBank U13945

Also Known As:

leukemia virus receptor, gibbon ape; GALV receptor; GLVR1; Glvr-1; Pit1 receptor; Pit2 receptor; amphotropic receptor pit-2; gibbon ape leukemia virus receptors; receptor, leukemia virus, gippon ape

Networked: 13 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Virus Receptors: 342
        gibbon ape leukemia virus receptor: 13

Experts

1.	Eiden, Maribeth V: 2 articles (01/2004 - 08/2002)
2.	Kasahara, N: 1 article (12/2013)
3.	Kubo, S: 1 article (12/2013)
4.	Logg, C R: 1 article (12/2013)
5.	Takagi-Kimura, M: 1 article (12/2013)
6.	Farrell, Karen B: 1 article (01/2004)
7.	Feldman, Steven A: 1 article (01/2004)
8.	Murthy, Ravi K: 1 article (01/2004)
9.	Russ, Jill L: 1 article (01/2004)
10.	Cheng, Heather H: 1 article (08/2002)

Related Diseases

1.	Starvation 07/01/2000 - "Phosphate starvation of target cells shows a two-fold increase in Pit2 receptor mRNA and causes some improvement in FLYA13 virus transduction efficiency. "
2.	Infections 08/01/2002 - "These data indicate that cofactor binding is not sufficient for FeLV-T infection and suggest that there may be a direct interaction between FeLV-T and the Pit1 receptor." 04/01/1995 - "The receptor specificity of Glvr2 for A-MLV could not be mapped to a single critical region; rather, N-terminal as well as C-terminal Glvr2-encoding sequences could confer specificity for A-MLV infection upon Glvr1. " 08/01/1994 - "All murine cells analysed to date have been found to be resistant to infection by GaLVs owing to the absence of a functional GaLV receptor. " 11/01/1993 - "Using LacZ retroviral pseudotypes and murine cells transfected with mutant GLVR1 expression vectors, we show that the same 9-amino-acid region of human GLVR1 is critical for infection by the three viruses. " 11/01/1993 - "Definition of a domain of GLVR1 which is necessary for infection by gibbon ape leukemia virus and which is highly polymorphic between species."
3.	Sarcoma (Soft Tissue Sarcoma) 12/01/1998 - "Simian sarcoma-associated virus fails to infect Chinese hamster cells despite the presence of functional gibbon ape leukemia virus receptors." 11/01/1993 - "The three type C retroviruses, gibbon ape leukemia virus (GALV), simian sarcoma-associated virus (SSAV), and feline leukemia virus subgroup B (FeLV-B), infect human cells by interacting with the same cell surface receptor, GLVR1. " 11/01/1993 - "Mutation of amino acids within the gibbon ape leukemia virus (GALV) receptor differentially affects feline leukemia virus subgroup B, simian sarcoma-associated virus, and GALV infections."
4.	Osteosarcoma (Osteogenic Sarcoma) 12/01/1997 - "In contrast to Pi uptake mediated by renal NaPi transporters, the activities of both the osteoblastic transport system and Glvr-1 are decreased at alkaline pH, and this observation led us to investigate expression of this transporter in human SaOS-2 osteosarcoma cells. "
5.	Mesothelioma 12/01/2013 - "Quantitative reverse transcription PCR demonstrated that ACC-MESO-1 cells express higher PiT-1 (GALV receptor) and lower PiT-2 (AMLV receptor) compared with normal mesothelial cells and other mesothelioma cells, presumably accounting for the distinctive finding that GALV-RRV replicates much more robustly than AMLV-RRV in these cells. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Phosphates (Orthophosphate)
3.	gibbon ape leukemia virus receptor
4.	Proteins (Proteins, Gene)
5.	Heterogeneous-Nuclear Ribonucleoprotein U
6.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7.	Transferases
8.	Virus Receptors
9.	Cell Surface Receptors
10.	Protein Kinase C