zalospirone

a partial 5-HT1A receptor agonist; RN given refers to (3aalpha,4alpha,4abeta,6abeta,7alpha,7aalpha)-isomer; RN for cpd without isomeric designation not available 4/91

Also Known As:

3a,4,4a,6a,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-etheno-1H-cyclobut(f)isoindole-1,3(2H)-dione; WY 47846; WY-47846; zalospirone dihydrochloride; zalospirone dihydrochloride, (3aalpha,4beta,4aalpha,6aalpha,7beta,7aalpha)-isomer; zalospirone hydrochloride

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - zalospirone: 1
  - Piperazines: 26
    - zalospirone: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - zalospirone: 1

Related Diseases

1.	Hypothermia 03/01/1993 - "At postsynaptic 5-HT1A receptors mediating hypothermia, eltoprazine, WY 48,723, MDL 72832 and tandospirone are agonists, zalospirone is a partial agonist and (-)-tertatolol, WAY 100,135, MDL 73005 EF and SDZ 216-525 are antagonists."

Related Drugs and Biologics

1.	SDZ 216-525
2.	eltoprazine
3.	binospirone mesylate
4.	MDL 72832
5.	tandospirone
6.	tertatolol (Artex)