OPC 15161

degradation product of OPC-15160; structure given in first source; superoxide inhibitor

Also Known As:

2(1H)-Pyrazinone, 6-(1H-indol-3-ylmethyl)-5-methoxy-3-(2-methylpropyl)-, 4-oxide; 6-(1H-indol-3-ylmethyl)-5-methoxy-3-(2-methylpropyl)-2-(1H)-pyrazinone 4-oxide; OPC-15161

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrazines: 150
    - OPC 15161: 2

Related Diseases

1.	Wounds and Injuries (Trauma) 09/01/1998 - "OPC-15161 may be useful in inhibiting the excessive fibrosis produced in the wound in response to filtering surgery."
2.	Nephritis 01/01/1997 - "In view of these results, we conclude that OPC-15161 notably ameliorated the urinary protein excretion by way of the suppression of lipid peroxidation in the renal tissue of NTS nephritis rats." 01/01/1997 - "The effects of OPC-15161, dipyridamole, and prednisolone on NTS nephritis rats were investigated. "
3.	Fibrosis (Cirrhosis) 09/01/1998 - "OPC-15161 may be useful in inhibiting the excessive fibrosis produced in the wound in response to filtering surgery."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Prednisolone (Predate)
3.	Dipyridamole (Persantine)

Related Therapies and Procedures

1.	Filtering Surgery