nuarimol

inhibits C14-demethylation in oat & rye sterol biosynthesis; RN given refers to cpd without isomeric designation

Also Known As:

Trimidal; alpha-(2-chlorophenyl)-alpha-(4-fluorophenyl)-5-pyrimidine methanol; nuarimol, (+-)-isomer

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Hepatomegaly 01/01/1996 - "In the case of both pesticides the effects observed consisted of hepatomegaly and hepatocyte proliferation (DNA synthesis and mitotic activity), although our studies indicated several distinct differences in the hepatic response between nuarimol, on the one hand and DDT on the other. "
2.	Necrosis 09/01/1994 - "The increase in binuclear hepatocytes and signs of necrosis suggested that the hepatomitogenic effect of nuarimol reflected a regenerative response, which may simulate the proliferation caused by partial hepatectomy." 01/01/1996 - "Moreover, DDT induced evident focal necrosis and abnormal mitoses whereas nuarimol caused only slight vacuolated cytoplasm. "

1.	Hepatectomy