1-(3-deoxypentofuranosyl)cytosine
structure given in first source
Also Known As:
1-(3-deoxy-beta-D-threo-pentofuranosyl)cytosine; 3'-deoxy-ara-C
Networked: 1
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Bio-Agent Context: Research Results
Related Diseases
| 1. | Neoplasms (Cancer)
02/01/1991
- " Among these compounds, 1-(3-deoxy-beta-D-threo-pentofuranosyl)cytosine (10, 3'-deoxy-ara-C) and 3'-deoxycytidine (22) had significant anticancer activity against CCRF-CEM, L1210, P388, and S-180 cancer cell lines in vitro, producing ED50 values of 2, 10, 5, and 34 microM, respectively, for 3'-deoxy-ara-C (10); and 25, 5, 2.5, and 15 microM, respectively, for 3'-deoxycytidine (22). "
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