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1- trichloromethyl- 1,2,3,4- tetrahydro- beta- carboline

structure given in first source

Also Known As:

1-TCMTC

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Carbolines: 283
      - 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline: 5
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Carbolines: 283
        1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline: 5
  - 3-Ring Heterocyclic Compounds
    - Carbolines: 283
      - 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline: 5

Experts

1.	Akundi, Ravi Shankar: 2 articles (11/2017 - 12/2003)
2.	Bringmann, Gerhard: 2 articles (11/2017 - 07/2006)
3.	Feineis, Doris: 2 articles (11/2017 - 07/2006)
4.	Fiebich, Bernd L: 2 articles (11/2017 - 12/2003)
5.	Chi, Lingyi: 1 article (01/2019)
6.	Guo, Hua: 1 article (01/2019)
7.	Hou, Xianzeng: 1 article (01/2019)
8.	Li, Jie: 1 article (01/2019)
9.	Liu, Zihao: 1 article (01/2019)
10.	Pang, Bo: 1 article (01/2019)

Related Diseases

1.	Neuroblastoma 11/01/2017 - "1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Alters Cell Cycle Progression in Human Neuroblastoma Cell Lines." 12/01/2003 - "1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) induces apoptosis in human neuroblastoma cell lines." 01/01/2012 - "Real-time monitoring of superoxide generation and cytotoxicity in neuroblastoma mitochondria induced by 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline."
2.	Pheochromocytoma 07/01/2006 - "The cytotoxicity of 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo, 4) to neuronal-like clonal pheochromocytoma PC12 cells was examined by the determination of lactate dehydrogenase (LDH) release. "
3.	Neuroinflammatory Diseases 01/01/2019 - "1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation."

Related Drugs and Biologics

1.	Superoxides (Superoxide)
2.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)